Heparin-induced thrombocytopenia (HIT) is caused by antibodies against a "self" protein-platelet factor 4-bound to heparin. We observed an overrepresentation of the female gender in 290 patients who developed HIT after cardiac or orthopedic surgery compared with the representation found in national databases (study 1). Therefore, we investigated gender imbalance in HIT by logistic regression an...

were analysed for wet and dry weight, total lipid, total, free and esterified cholesterol, total carboxyl ester, lipid phosphorus and triglyceride. The translocated testes decreased in wet and dry weight (P<0\m=.\001) and total lipid content (P< 0\m=.\001)6 days after surgery. Lipid concentration increased (P<0\m=.\01)in translocated testes, as did concentrations of total cholesterol (P<0\m=.\0...

STUDY OBJECTIVE This randomized, placebo-controlled trial evaluates the analgesic efficacy and safety of intravenous single-dose paracetamol and morphine for the treatment of renal colic. METHODS We conducted a randomized, double-blind, placebo-controlled clinical trial comparing single intravenous doses of paracetamol (1 g), morphine (0.1 mg/kg), and placebo (normal saline solution) for pati...

Results The prevalence of various pregnancy complications was 8. 6% for birth prematurely, 9. 2% for hypertension or preeclampsia, IUGR 5. 8% and 7. 3% for loss pregnancy. PAPP A levels were lower in fetal loss group (P = 0. 005), vascular disease group(P = 0. 001) and preterm delivery group(P = 0. 001). In addition, a lower rate of bHCG was associated with the occurrence of placental pathologi...

OBJECTIVES Comprehensive school health (CSH) is a multifaceted approach to health promotion. A key objective of CSH is to foster positive health behaviors outside of school. This study examined the 2-year change in physical activity during and after school among students participating in a CSH intervention in Edmonton, Alberta, Canada. METHODS This was a quasi-experimental, pre-post trial wit...

A double-blind randomized clinical trial was performed in 6- to 7-yr-old schoolchildren to evaluate, in a 30-mo period, whether the caries increment on the distal surface of the second primary molars adjacent to permanent first molars sealed with fluoride release compounds would be lower with respect to those adjacent to permanent first molars sealed with a nonfluoridated sealant. In sum, 2,776...

PURPOSE To assess the feasibility of a new intervention, Ready~Steady, in terms of demand, acceptability, implementation, and limited efficacy. DESIGN Randomized controlled trial; repeated measures. SETTING Two rural communities in Itasca County, Minnesota. SUBJECTS Thirty participants were randomized to an intervention (n = 16) or attention-control (n = 14) group. INTERVENTION Ready~St...

UNLABELLED Our purpose was to evaluate changes in cadaveric donor factors between 1993 and 2004 and their impact on the short- and long-term outcomes of renal transplants in a single center. PATIENTS AND METHODS Cadaveric renal transplants performed in our unit between 1993 and 2004 were divided in two groups of identical length: A (n = 455; 1993-1998) and B (n = 465; 1999-2004). Major differ...

UNLABELLED Little is known about the relationship between attitudes and characteristics of instructors and uptake and adherence of older people to exercise classes. This article explores these issues. METHODS The authors surveyed 731 UK exercise instructors with specialist older adult exercise qualifications. A questionnaire investigated instructors' characteristics and attitudes toward older...