Fluomine is a cobalt chelate compound which complexes molecular oxygen and releases it on heating. This property has led to its use a a regenerable oxygen source in high-altitude aircraft. Investigations into the acute effects of exposure to fluomine by various routes were undertaken as first steps in the toxicological characterization of the material. Single-dose rat and mouse oral administrat...

The effects of inhaled zinc oxide/hexachloroethane smoke (11,580 mg x min/m3) and intratracheally instilled zinc chloride (2.5 mg/kg body weight) have been studied in rat lung. The effects of subsequent treatment with 70% oxygen have been studied after both procedures. Both the inhalation of the smoke and instillation of zinc chloride produced similar effects that included pulmonary edema, alve...

Background Joint punctures in children require adequate analgesia, sedation or both. Suitable for this are intravenous sedatives (eg propofol, midazolam) and analgetics (eg, ketamine and fentanyl). The use of these substances is safe, but requires an intravenous line, monitoring and followup. Nitrous oxide/oxygen (N2O/O2) sedation has a long-standing history of safety and success. N2O/O2 has an...

An infant is described who presented a complex cardiopulmonary problem which was evaluated with the help of new physiological techniques. the infant was born at term after an emergency Caesarian section for fetal distress and was found to have meconium aspiration. He remained persistently tachypnoeic and hypoxic despite high ambient oxygen. Chest radiography suggested cystic lesions at the lung...

Hospitalized preterm infants are exposed to stressful stimuli and early parental separation, which can undermine their long-term development mother-infant bonding. Family-centered music therapy enable positive interactions, mediated by maternal infant-directed singing. This study aimed investigate the effects of on infant’s signs engagement, namely Eye Opening (EO) Smiling (SM), vocalizations. ...

The emergence of multidrug-resistant (MDR) pathogens within biofilms in the cystic fibrosis lung results increased morbidity. An inhalation therapy derived from alginate, OligoG CF-5/20, is currently clinical trials for patients.

A 3-month-old infant of 33 weeks' gestation was hospitalized with pneumonia caused by Bordetella pertussis. Respiratory insufficiency worsened, and on hospital day 3, there was severe pulmonary dysfunction (arterial oxygen pressure/fraction of inspired oxygen ratio: 120), extreme leukocytosis (white blood cell count 104,000/mm3), and severe pulmonary hypertension as assessed by 2-dimensional ec...

OBJECTIVE To determine the impact of speech therapy on asthma and allergic rhinitis control in mouth breathing children and adolescents. METHODS This was a quasi-experimental randomized study of 24 mouth breathing patients with asthma and allergic rhinitis, aged from 6 to 15 years. All patients were taking beclomethasone diproprionate through oral inhalation at the start of the study. At enro...

BACKGROUND The aim of this study was to investigate the postoperative hemodynamic effects of nitroglycerin inhalation on patients with pulmonary hypertension undergoing mitral valve replacement surgery. METHODS Twenty patients who underwent mitral valve replacement surgery were included in the study. In the surgical intensive care unit, at T0 (before the inhalation of nitroglycerin), basal sy...

January-February 2015 The Surfactant, Positive Pressure, and Oxygenation Randomized Trial (SUPPORT) has been the focal point of many different criticisms regarding the ethics of the study ever since publication of the trial’s findings in 2010 and 2012. These criticisms center on two major concerns. The first concern rests on a belief that, when the SUPPORT study was being designed, the state of...