Objectives: Hypoxia results from the unavailability of sufficient oxygen to tissues. Since previous studies have shown that hypoxia in inflammation, this research has found it necessary investigate impact chronic on lungs and blood mice also potential benefit minocycline which is a well-known antibiotic.
 Design: Thirty were split into 5 groups 6 animals each. A physical model was used. He...

UNLABELLED The effects of anesthesia on ischemia-reperfusion injury are of considerable scientific and clinical interest. We examined the effects of propofol (known to possess antioxidant activity) and halothane (devoid of antioxidant activity in vitro) on tissue and red blood cell (RBC) antioxidant capacity. Adult male Wistar rats were anesthetized with halothane 0.5%-1.0% (n = 7), propofol 50...

BACKGROUND Hypercapnic acidosis frequently occurs when patients with acute lung injury are initially ventilated with low tidal volume "protective" strategies. Hypercapnic acidosis per se, in the absence of any change in tidal volume or airway pressure, is protective when instituted before the onset of injury. However, the mechanisms by which hypercapnic acidosis confers this protection are inco...

We have recently shown that a combination of vitamin A (VA) and retinoic acid (RA) in a 10:1 molar ratio (VARA) synergistically increases lung retinoid content in newborn rodents, more than either VA or RA alone in equimolar amounts. We hypothesized that the increase in lung retinoids would reduce oxidative stress and proinflammatory cytokines, resulting in attenuation of alveolar simplificatio...

The number of electronic smokers has increased annually. Exposure to an cigarette will increase free radicals in the body and result oxidative stress causing lung tissue damage. severity degree damage caused by smoke exposure depends on duration exposure, affect Matrix Metalloproteinase-8 collagen type-2 cells. study aims understand change type-2in due exposure. This applied experimental method...

Cadmium (Cd) is a heavy metal toxic that can cause health problems including lung injury. This study was set out to meet the growing demand for effective treatment of diseases and explore mechanism caffeic acid phenethyl ester (CAPE, natural phenolic acid) protect against Cd-caused damage. In this study, CAPE significantly increased mice body weight, decreased W/D ratio, alleviated histomorphol...