background: recurrent aphthous stomatitis (ras) is the most common inflammatory ulcerative condition of oral cavity. the aim of this study was to compare the levels of the salivary malondialdehyde (mda) and total antioxidant capacity (tac) and blood parameter in ras versus healthy controls. methods: this case-control study consisted of 28 patients with ras and 28 age and sex -matched control wi...

OBJECTIVES This study was aimed to investigate the protective effects of dexpanthenol (Dxp) on against cisplatin-induced ototoxicity. METHODS To examine this effect, distortion product otoacoustic emissions (DPOAEs) measurements and serum levels of oxidative and antioxidant status (including malondialdehyde, superoxide dismutase, catalase, glutathione, glutathione peroxidase, total oxidant st...

INTRODUCTION Obstructive sleep apnea (OSA) is one of the most prevalent sleep disorders. In the present study, we assessed the nitrite level, which is an indirect indicator of nitric oxide (NO), total oxidant status (TOS), total antioxidant status (TAS) and oxidative stress index (OSI), which may be associated with endotel dysfunction. We investigated the difference between the groups and the r...

Evidence of in vivo oxidant-induced injury in inflammatory bowel disease (IBD) is largely indirect. Colon epithelial crypt cells (CEC) from paired specimens of histologically normal and inflamed bowel from IBD patients with active disease were examined for altered protein thiol redox status as an indicator of oxidative damage. When CEC preparations from 22 IBD patients were labeled with the red...

INTRODUCTION Acrolein (2-propenal) is a reactive α, β-unsaturated aldehyde which causes a health hazard to humans. The present study focused on determining the protection offered by sulforaphane against acrolein-induced damage in peripheral blood mononuclear cells (PBMC). MATERIAL AND METHODS Acrolein-induced oxidative stress was determined through evaluating the levels of reactive oxygen spe...

BACKGROUND The induction of the pneumoperitoneum increases intraabdominal pressure (IAP), causing splanchnic ischemia, whereas its deflation normalizes IAP and splanchnic blood flow. We investigated the oxidant-antioxidant status of dogs who underwent low pressure (7 mm Hg), standard pressure (12 mm Hg), and high pressure (15 mm Hg) pneumoperitoneum. RESULTS Twenty-four beagle dogs (12 males ...

Imbalance in oxidant and antioxidant status is one of the commonly observed phenomenon in several pathological conditions including cancer. Also, defect in detoxification cascade leads to accumulation of toxic metabolites, which cause mutation in DNA and leads to neoplastic transformation. Aim of the present study is to focus the chemopreventive potential of Adhatoda vasica leaves during DMBA i...

Rheumatoid arthritis (RA) is a chronic condition which major contributor to disability in older adults. The cornerstone of rheumatoid care now disease-modifying antirheumatic medication. most widely used medication among these hydroxychloroquine, has been shown have antioxidant properties and delay the course illness. Thus, current study's objective compare oxidant status RA patients Mosul ...