Abstract We image the spatial extent of a cool galactic outflow with fine-structure Fe ii * emission and resonant Mg in gravitationally lensed star-forming galaxy at z = 1.70347. The (continuum-subtracted) emissions span out to radial distances ∼14.33 26.5 kpc, respectively, maximum extents ∼21 kpc for ∼30 emission. is patchy covers total area ∼184 2 , constraining minimum covered by outflowing...

Like all fluids, blood tends to flow from areas of high pressure to low pressure. This seemingly trite observation hides a great deal of sophisticated pathophysiology that we are only beginning to exploit diagnostically and potentially therapeutically. In this issue of Circulation, Yotti and colleagues have exploited a new noninvasive technique to measure the small pressure differences generate...

Edmund Kenneth Kerut, M.D.,∗ Curtis Hanawalt, R.D.C.S.,† Marie Dearstine, R.D.C.S., ‡ Robert Frank, M.D.,§ and Charles Everson, M.D.§ ∗Heart Clinic of Louisiana, Marrero, Louisiana, Departments of Physiology and Pharmacology, LSU Health Sciences Center, New Orleans, Louisiana, †Cardiac and Vascular Imaging Center, West Jefferson Medical Center, Marrero, Louisiana, ‡Cardiology Department, Ochsne...

Aqueous humor outflow resistance is the primary determinant of intraocular pressure (IOP), and increased outflow resistance is the basis for elevated IOP associated with glaucoma. Experimental evidence suggests that the bulk of outflow resistance is generated in the vicinity of the inner wall endothelium of Schlemm's canal, its basement membrane and the juxtacanalicular connective tissue (JCT)....

The effect of corticosteroids on aqueous humor (AH) formation rate and outflow facility was measured in the cat eye. AH formation rate was determined by continuous posteroanterior chamber perfusion with an AH-like buffer containing inulin-C*. It was found that the total quantity of inulin-C recovered through the anterior chamber outflow cannula could be used to estimate changes in outflow facil...

[1] Ionospheric outflow has been shown to be a significant contributor to the plasma population of the magnetosphere during active geomagnetic conditions. We present the results of new efforts to model the source and effects of out-flowing plasma in the Space Weather Modeling Framework (SWMF). In particular, we develop and use the Polar Wind Outflow Model (PWOM), a field-aligned, multifluid, mu...

Aqueous humor outflow resistance was studied in monkeys (Cercopithecus ethiops) with intact oculomotor nerves, after the nerve had been severed on one side, and during electrical stimulation of the severed nerve. Pupil diameters (on both eyes) and outflow resistance on the non-stimulated side acted as controls. It was found that the outflow resistance increased and the pupil dilated when the ne...

Cardiac power (PWR) is the continuous product of flow and pressure in the proximal aorta. Our aim was to validate the PWR integral as a marker of left ventricular energy transfer to the aorta, by comparing it to stroke work (SW) under multiple different loading and contractility conditions in subjects without obstructions in the left ventricular outflow tract. Six pigs were under general anesth...

: A 55-year-old gentleman with hypertrophic obstructive cardiomyopathy and heart failure symptoms underwent cardiac catheterization, which confirmed a significant pressure drop (60 mmHg) across the left ventricular outflow tract, a double-peaked pulse (pulsus bisferiens) and an absent postextrasystolic potentiation (Brockenbrough-Braunwald-Morrow sign) in the left ventricular outflow tract and ...

The relation to the pressure gradient as assessed by echocardiography and the CMR-derived planimetry of the LVOT is not known, no values for the differentiation of obstruction exist. We studied 37 patients with hypertrophic cardiomyopathy and 14 healthy controls using standard sequences with 3D coverage of the left ventricular outflow tract. A cutoff value of 2.7 cm2 identified obstruction as d...