Osseous grafting represents one mode of therapy to manage periodontal osseous defects. Materials for osseous grafting can be obtained from the same person (autografts), from a different person of the same species (allografts), from a different species (xenografts), or from synthetic materials (alloplasts). The two types of grafts most frequently used in periodontal therapy are autogenous grafts...

Bone disorders are of significant worry due to their increased prevalence in the median age. Scaffold-based bone tissue engineering holds great promise for the future of osseous defects therapies. Porous composite materials and functional coatings for metallic implants have been introduced in next generation of orthopedic medicine for tissue engineering. While osteoconductive materials such as ...

Bone fusion represents a challenge in the orthopedics practice, being especially indicated for spine disorders. Spinal fusion can be defined as the bony union between two vertebral bodies obtained through the surgical introduction of an osteoconductive, osteoinductive, and osteogenic compound. Autogenous bone graft provides all these three qualities and is considered the gold standard. However,...

Coatings of orthopedic implants are investigated to improve the osteoinductive and osteoconductive properties of the implant surfaces and thus to enhance periimplant bone formation. By applying coatings that mimic the extracellular matrix a favorable environment for osteoblasts, osteoclasts and their progenitor cells is provided to promote early and strong fixation of implants. It is known that...

The role of bone-graft extenders in impaction revision surgery is becoming increasingly important. Tricalcium phosphate and hydroxyapatite have been shown to be both biocompatible and osteoconductive, yet many surgeons remain reluctant to use them. The difficulty in handling bone-graft extenders can be partly alleviated by using porous particles and adding clotted blood. In an in vitro model we...

Calcium phosphate has been widely used in bone regeneration applications. Originalkalsium fosfat merupakan biomaterial yang sering diaplikasikan ke dalam defek tulang dengan tidak memberikan efek toksik pada jaringan sehat.The most commonly calcium are hydroxyapatite and β-tricalcium (β-TCP). β-TCP is one of the bioceramic materials that chemical structure β-Ca3(PO4)2. The use medicine dentistr...

Osteoconductive function is remarkably low in bone disease the absence of tissue surrounding grafting site, or if poor condition. Thus, an effective graft terms both osteoconductivity and osteoinductivity required for clinical therapy. Recently, three-dimensional (3D) kagome structure has been shown to be advantageous regeneration due its mechanical properties. In this study, a polycaprolactone...

Calcium phosphate cements (CPCs) are attractive synthetic bone grafts as they possess osteoconductive and osteoinductive properties. Their biomimetic synthesis grants them an intrinsic nano- microporosity that resembles natural is paramount for biological processes such protein adhesion, which can later enhance cell adhesion. However, a main limitation of CPCs the lack macroporosity, crucial to...

The design of scaffolds with multifunctional properties is attractive for tissue engineering due to their potential provide and improve the quality life people who require surgery or have bone diseases defects. these applications must be bioactive comply effects biocompatibility biodegradability. They also promote osseointegration facilitate formation on its surface allow adhesion surrounding l...

Scaffolds of PDLLA were produced to be implemented in maxilofacial surgeries inducing bone repair and regeneration. To prepare these scaffolds, bioglass (BG58S) was synthesized by sol-gel method, in order to be applied as osteoconductive dispersed particles in PDLLA matrix. Once presenting greater facility on parts fabrication, this polymeric matrix enables complex geometries production besides...