this evidence-based article reviews risk indicators and management of unknown-origin xerostomia. xerostomia and hyposalivation refer to different aspects of dry mouth. xerostomia is a subjective sensation of dry mouth, whilst hyposalivation is defined as an objective assessment of reduced salivary flow rate. about 30% of the elderly (65 years and older) experience xerostomia and hyposalivation....

in order to identify the pressure patterns causing the cold weather over the northwestern iran, daily lowest temperatures of six stations of the study area during january- march months of the 1986-2003 period were obtained from meteorological organization of islamic republic of iran (irimo) in the quality controlled format. according to the defined threshold, the very cold days were extracted a...

islamic mysticism or sufism is one of the most outstanding appearances of islamic culture that has had a fundamental and undeniable role in the history of islam. a careful study of the history and development of the movements of islamic culture shows that this movement, like most other ones, has been originated from, developed, and cultivated in an islamic environment, though it has undoubtedly...

Despite intense investigation, human replication origins and termini remain elusive. Existing data have shown strong discrepancies. Here we sequenced highly purified Okazaki fragments from two cell types and, for the first time, quantitated replication fork directionality and delineated initiation and termination zones genome-wide. Replication initiates stochastically, primarily within non-tran...

The initiation of DNA replication in eukaryotic cells at the onset of S phase requires the origin recognition complex (ORC) [1]. This six-subunit complex, first isolated in Saccharomyces cerevisiae [2], is evolutionarily conserved [1]. ORC participates in the formation of the prereplicative complex [3], which is necessary to establish replication competence. The ORC-DNA interaction is well esta...

OBJECTIVE The aim of this study is to compare the each clinical manifestation related with its mean survival time of Krukenberg tumors (KTs) of gastric origin versus with that of colorectal origin. METHODS A total of 156 consecutive patients diagnosed with KTs of the ovary who underwent surgical treatment at a single institution between 2001 and 2010 were retrospectively evaluated. Each clini...