Much is known about the composition and function of the postsynaptic density (PSD), but less is known about its molecular organization. We use EM tomography to delineate the organization of PSDs at glutamatergic synapses in rat hippocampal cultures. The core of the PSD is dominated by vertically oriented filaments, and ImmunoGold labeling shows that PSD-95 is a component of these filaments. Ver...

Model driven development for software systems provides us with many advantages in quality, productivity, or reusability. For accurate modeling, we have to create many kinds of models from various viewpoints. When applying model driven development to enterprise information systems, those viewpoints include not only software oriented matters but also business oriented matters. Such complexity in ...

The study is an attempt to propose the criteria for determining the appropriate connectivity of ERP systems. The result of this study provides a framework assisting ERP adopters in selecting integration approach which are appropriate to their needs. A survey was conducted to obtain information from ERP users to learn about their opinions on factors and criteria affecting connectivity of ERP sys...

Along which basic lines could an organization which plans to invest in knowledge management proceed? What general initiatives can be suggested for knowledge management? First, an array of knowledge management goals and strategies is presented taken from theoretical and empirical studies which are then related to each other in the light of what we call a strategic intervention into an organizati...

We present a longitudinal project using action design research, which is a four-year collaboration between two EPFL entities: The research Laboratory for Systemic Modeling (LAMS) and EPFL’s IT department, called the VPSI. During that time the VPSI was going through a transformation into a service-oriented organization. The research project began as an open-ended modeling of some of the VPSI pro...

To control complicated and decomposable networking functions, such as Diffserv, two or more policies must cooperate. Combining two or more mutually dependent policies for a specific purpose is called policy combination. Methods of passing information between combined policies can be classified into real tags and virtual tags, or labels and attributes. Policy combinations can be classified into ...

This chapter introduces an agent-oriented enterprise model for conducting enterprise modeling during the early stages of information system requirements engineering. The enterprise model integrates a set of concepts and relationships that the analyst instantiates when building a model of the part of the organization in which the future information system will operate. The aim is to allow the an...

Multidisciplinary rounds (MDR) have become important mechanisms for communication and coordination of care. To guide design of tools supporting MDR, we reviewed the literature published from 1990 to 2005 about MDR on information tools used, information needs, impact of information tools, and evaluation measures. Fifty-one papers met inclusion criteria and were included. In addition to patient-c...

As we all know that many different kind of organization need database for required information from different area like analytic, different types of reports and other many reasons. As the organization grows the database also grow into millions of records spared over many tables and business intelligent/science. And if any organization want any specific report strategic analysis, and other busin...

Virtual Organizations in a dynamic environment need efficient methods of change management to initiate changes to partners’ services. In this paper, the authors present a structural and a procedural framework for change management in Service-Oriented Virtual Organizations. The structural framework categorizes changes into three layers of change and identifies triggers of changes. The procedural...