In this investigation, sensitive and reproducible methods are described for quantitative determination of deflazacort in the presence of its degradation product. The method was based on high performance liquid chromatography of the drug from its degradation product on reverse phase using Acquity UPLC BEH C18 columns (1.7 µm, 2.1 mm × 150 mm) using acetonitrile and water (40:60 V/V) at a flow ra...

The physicochemical stability of an aqueous, phospholipid-based dispersion of itraconazole microcrystals was studied as a model water-insoluble drug suspension. The particle size, phospholipid concentrations, free fatty acid (FFA) content, pH, and zeta potential of two test suspensions were followed over 63 days at 5 and 40 degrees C storage conditions. Hydrolysis of a control suspension contai...

A simple, linear gradient, rapid, precise and stability-indicating RP-UPLC method was developed for the determination of Cloxacillin Sodium in its bulk form and formulation. Ultra performance liquid chromatography, a most promising advancement in a world of chromatography, reduces analysis time, increases reliability through higher resolution, sensitivity and selectivity as well as used as an e...

Feruloylacetone (FER) is a natural degradant of curcumin after heating, which structurally reserves some functional groups curcumin. It not as widely discussed its original counterpart has been previously; and in this study, anticancer efficacy investigated. This study focuses on the suppressive effect FER colon cancer, efficacious typical cancer type well evidenced. In addition, demethoxy-feru...

in this paper, we generalize some results from hilbert c*-modules to pro-c*-algebra case. we also give a new proof of the known result that l2(a) is ahilbert module over a pro-c*-algebra a.

This study investigates whether and how the demand for animal-friendly pork can benefit from individual joint use of label “Animal Friendly,” “Organic,” “Local,” “Low Fat.” A choice experiment was conducted to collect data. The data were analyzed using random parameter logit latent class models. Three consumer segments identified. Consumers in Segment 1 (pro-welfare consumers—39% all respondent...

The design of peptidomimetics able to mimic the structural and binding motifs of proteins is a major challenge in the development of new pharmaceutical tools. The b-turn motif is one of the major secondary structure elements that plays an important role in the folding of globular proteins and is often implicated as a recognition element in receptor–ligand interactions. Considerable effort has b...