A complication in the analysis of the role of ICP34.5 gene in the herpes simplex virus type-1 (HSV-1) lifecycle is the presence of overlapping antisense gene, open reading frame P (ORF P), which is also deleted in HSV-1 ICP34.5 negative mutants. A HSV-1 wild type strain (17) ICP34.5/ORF P deletion mutant (1716) is totally avirulent in animal models and impaired in a number of in vitro functions...

Quantum mechanical effects related to the recently developed projective theory of relativity are considered. It is shown that at cosmological time intervals the light velocity increases and the atomic units of length and time are shrinking. A new derivation of the Hubble Law is presented.

With rapidly increasing herd sizes, focus on contagious udder pathogens becomes important. Based on a yearly test of bulk tank milk in Danish dairy herds, the prevalence of herds infected with Streptococcus agalactiae (S. agalactiae) increased from 2 % in 2000 to 7 % in 2010, while approximately 90 % of the herds were positive for Staphylococcus aureus (S. aureus) (Katholm, et al., 2012). The r...

When we think of the word ‘‘contagious,’’ we often think of something negative, like the flu. But transmitted diseases aren’t the only thing that can quickly spread within a society—certain feelings, emotions, and behaviors can be easier to catch than the common cold. Does seeing others laugh or yawn make you want to do it too? You’re definitely not alone—‘‘behavioral contagion,’’ or the tenden...

DNA from isolates of monkeypox virus, when digested with the endonuclease PstI, gave fragment-size profiles which correlated with the geographic area from which the isolate originated. Although some of the differences were located subterminally in the genome, others mapped to the central conserved region. Further differentiation of the viral genomes was sought by analysis of a short region with...

BACKGROUND The major psychoactive cannabinoid compound of marijuana, delta-9 tetrahydrocannabinol (THC), has been shown to modulate immune responses and lymphocyte function. After primary infection the viral DNA genome of gamma herpesviruses persists in lymphoid cell nuclei in a latent episomal circular form. In response to extracellular signals, the latent virus can be activated, which leads t...

The genome of a novel virus of the house cricket consists of a 2,517-nucleotide (nt) circular single-stranded DNA (ssDNA) molecule with 4 open reading frames (ORFs). One ORF had a low identity to circovirus nucleotide sequences (NS). The unique properties of this volvovirus suggested that it belongs to a new virus family or genus.

We present a theoretical approach which allows to determine the number and orbital character of the conducting channels in metallic atomic contacts. We show how the conducting channels arise from the atomic orbitals having a significant contribution to the bands around the Fermi level. Our theory predicts that the number of conducting channels with non negligible transmission is 3 for Al and 5 ...

BACKGROUND Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8, may be the infectious cause of KS. Its prevalence in the general population, on the basis of detection of the virus genome, is controversial. To investigate the seroprevalence, we measured antibodies to a recombinant capsid-related (lytic cycle) KSHV antigen and a latent antigen complex. METHODS We s...