This review is based on recently published data from our laboratory. We investigated the role of hypertension and laminar flow, hypercholesterolemia and laminar flow and turbulent blood flow/low wall shear stress, and turbulent blood flow/low wall shear stress associated with hypercholesterolemia on aorta remodeling of rats feeding normal diet or hypercholesterolemic diet. Our findings suggest ...

A three-dimensional computer model of human aortic arch with three branches is reproduced to study the pulsatile blood flow with Finite Element Method. In specific, the focus is on variation of wall shear stress, which plays an important role in the localization and development of atherosclerotic plaques. Pulsatile pressure pulse is used as boundary condition to avoid flow entry development, an...

BACKGROUND AND PURPOSE Saccular intracranial aneurysm is a common disease that may cause devastating intracranial hemorrhage. Hemodynamics, wall remodeling, and wall inflammation have been associated with saccular intracranial aneurysm rupture. We investigated how saccular intracranial aneurysm hemodynamics is associated with wall remodeling and inflammation of the saccular intracranial aneurys...

In this paper, nonlinear behavior of strengthened steel plate shear walls (SPSWs) by FRP laminates theoretically and numerically has been investigated. In the first part, a new method, “the composite-plate frame Interaction (C-PFI) method”, has been introduced to predict the shear behavior of the composite steel plate shear wall systems (CSPSWs). In the second part, several models of one-story ...

Particle image velocimetry (PIV) has been gaining acceptance as a routine tool to evaluate the flow fields associated with fluid mechanical devices. We have developed algorithms to investigate the wall shear-rates within the 50cc Penn State artificial heart using low magnification, conventional particle image velocimetry (PIV). Wall shear has been implicated in clot formation, a major post-impl...

Received Mar 10, 2016 Revised May 12, 2016 Accepted May 24, 2016 This study focuses on the behavior of blood flow through diseased artery in the presence of porous effects. The laminar, incompressible, fully developed, non-Newtonian in an artery having axially non-symmetric but radially symmetric stenosis is numerically studied. Here blood is represented as Herschel-Bulkley fluid model and flow...

The complexity of the skewed 3-D boundary layer (figure 3) necessitates the use of multiple coordinate systems. The Tunnel coordinate system is right-handed with the x-axis parallel to the tunnel centerline pointing downstream and the y-axis perpendicular to the tunnel floor pointing up. The Wall-Shear-Stress coordinate system is right-handed with the x-axis in the shear-stress direction at the...

In this paper, the Al2O3-water nanofluid flow in laminar and turbulent flows inside tubes fitted with diamond-shaped turbulators is numerically modeled. The nanofluid flow is modeled by employing a two-phase mixture method and applying the constant heat flux boundary condition at tube walls. In the results, the effects of different parameters such as the geometry of turbulators, volume fraction...

Metal spinning as a kind of manufacturing process has capability to shape hollow components. In present work shear spinning process is used to formplates into conical shapes. Moreover, the aim of this research is to demonstrate the impact of the process parameters (i.e. feeding rate and spindle speed) on wall thickness. This approachwas done by experimental and finite elements method. The resul...

When using shear testing to determine wall friction of pharmaceutical particulate systems, it is crucial to measure at the correct wall normal stress. By comparing data obtained at a wall normal stress of 1000 to 200 Pa, the effect of the applied stress on the accuracy and precision of the method was assessed. INTRODUCTION When powder flows under gravity from a hopper, it follows one of two pat...