In patients with portal hypertension, plasma insulin levels were raised both fasting and after oral glucose or intravenous tolbutamide. This supports previous suggestions that resistance to endogenous insulin plays a major role in producing the impaired glucose tolerance found in chronic hepatic dysfunction. The operation of portacaval anastomosis was followed by impaired oral fructose toleranc...

as the incidence of obesity increases, less invasive weight loss methods rather than bariatric surgery will be needed. this article reviews the advances in endoscopy, results, benefits and side effects of these techniques for treating obesity. the endoscopic options for weight loss could be broadly grouped under the following categories: restriction procedures, malabsorption procedures, and neu...

Parathyroid hormone-related protein (PTHrP) is detected in many aggressive tumors and involved in malignant conversion; however, the underlying mechanism remains obscure. Here, we identified PTHrP as a mediator of epidermal growth factor receptor (EGFR) signaling to promote the malignancies of oral cancers. PTHrP mRNA was abundantly expressed in most of the quiescent oral cancer cells, and was ...

I Siewert M, Gnekow H. Uber die Stabilitat von Glucose-Elektrolyt-Mischungen (oral rehydration salts: ORS) zur Therapeutie von Durchfallerankungen). Phartnazeutische Zeitung 1983;128: 1169-74. 2 Hoffman SL, Moechtar MA, Simajutank C, et al. Rehydration and maintenance therapy of cholera patients in Jakarta: citrate-based versus bicarbonate-based oral rehydration salt solution. J Infect Dis 1985...

The responses of single parabrachial nucleus (PBN) neurons were recorded extracellularly to characterize their sensitivity to stimulation of individual gustatory receptor subpopulations (G neurons, n = 75) or mechanical stimulation of defined oral regions (M neurons, n = 54) then localized to morphologically defined PBN subdivisions. Convergence from separate oral regions onto single neurons oc...

Motor fluctuations and dyskinesia in later stages of Parkinson's disease (PD) are caused by pharmacokinetic as well as pharmacodynamic factors, intermittent dopaminergic stimulation being one of the most important. In the healthy brain, dopamine neurons in the substantia nigra pars compacta fire tonically at a steady rate of about 4 cycles/second. In later stages of PD, steady firing is replace...

the use of deep brain stimulation in psychiatric disorders has received great interest owing to the small risk of the operation, the reversible nature of the technique, and the possibility of optimizing treatment postoperatively. currently deep brain stimulation in psychiatry is investigated for obsessive-compulsive disorder, gilles de la tourette’s syndrome and major depression. this presentat...

background: the preparation of endometrium for embryo reception is dependent on the ovarian hormones, which are affected by ovarian hyperstimulation procedure. objective: the aim of this study was to evaluate the changes in morphometrical indices of endometrium by the daily injection of progesterone after mouse ovarian induction. materials and methods: adult virgin female mice were selected and...

As society ages the number of dysphagia patients and elderly people who cannot independently manage oral care will also increase. Maintaining or improving proper swallowing and oral functions is an important issue from the perspective of retaining quality of life (QOL) and motivation in living. Dysphagia patients are susceptible to aspiration pneumonia, and are also more likely to be malnourish...