Whole gut perfusion in humans was used to compare the effect on intestinal water and electrolyte transport of the World Health Organisation oral rehydration solution (solution II, composition in mmol/l: glucose 111, sodium 90, bicarbonate 30, potassium 20; 308 mOsm/kg); a hypertonic commercial oral rehydration solution (solution III, glucose 188, sodium 50, bicarbonate 20, potassium 20 mmol/l; ...

Background: The administration of pediatric medicines in an accurate manner for successful therapy is imperative. This study aimed to investigate the Iran Medicine List for the appropriateness of the six pharmacological formulations for children populations to the success of accurate dose delivery. <span style="f...

BACKGROUND Diarrhea remains to be a main cause of childhood mortality. Diarrhea case management indicators reflect the effectiveness of child survival interventions. We aimed to assess time trends and country-wise changes in diarrhea case management indicators among under-5 children in low-and-middle-income countries. METHODS We analyzed aggregate data from Demographic and Health Surveys and ...

Sir, In their review of acquired toxoplasmosis in children, McNicholl and Flynn (Archives, 1978, 53, 414) suggest the use of sulphadimidine and pyrimethamine for treatment of generalised toxoplasmosis. We report a child with generalised toxoplasmosis who had a dramatic recovery after treatment with co-trimoxazole. An 1 1i-year-old girl presented to the hospital with an 8-week history of weight ...

BACKGROUND Diarrhoeal diseases cause significant childhood morbidity and mortality worldwide. The effectiveness of home management of diarrhoeal diseases is achievable only if caregivers have appropriate information despite varying recommendations on the strategies for diarrhoea therapy. OBJECTIVES To evaluate caregivers' perception and use of ORT fluids for management of diarrhoea in under-f...

We evaluated the safety and efficacy of a glycine-based orally administered rehydration solution by comparing it with a standard oral rehydration solution (ORS) without glycine in a randomized double-blind trial in United States infants (age less than 15 months) given treatment for acute gastroenteritis as inpatients or outpatients. The response to therapy (stool volume and duration of illness)...