Oral dryness is common among aging individuals and its objective evaluation is an important issue for improving their oral health. In the present study, we measured the objective mucosal moisture in elderly individuals with a moisture checker and evaluated its relation with laboratory findings and subjective oral status. The subjects were 502 adults (244 men and 258 women), with a mean age of 7...

AIMS To assess keratin profiles from smears of malignant and contralateral normal oral mucosa as part of the development of a screening procedure for oral cancer based on exfoliative cytology. METHODS Smears were taken from oral cancers (confirmed by biopsy) and from the contralateral site of 20 patients. Using a panel of antikeratin antibodies, the keratins expressed by these cells were iden...

Malignant melanoma of the oral cavity is a rare tumor that occurs due to uncontrolled growth melanocytes found in basal layer mucous membranes. Majority melanomas occur maxilla, especially on keratinizing mucosa palate and gingiva. Clinically have different types like pigmented nodular type, macular mixed non-pigmented type type. Here, we present case report 57 year old female patient with muco...

Head and neck cancer is one of the most prevalent cancers in the world. Roughly half of these malignancies originate from oral mucosa and constitute oral squamous cell carcinomas. Despite many advances in diagnostic and therapeutic regimens, five-year survival rate remains at roughly 50%, indicating the need for in depth understanding of the oral squamous cell carcinoma immunobiology. We have p...

Human and simian immunodeficiency virus (HIV and SIV) infections are characterized by manifestation of numerous opportunistic infections and inflammatory conditions in the oral mucosa. The loss of CD4(+) T cells that play a critical role in maintaining mucosal immunity likely contributes to this process. Here we show that CD4(+) T cells constitute a minor population of T cells in the oral mucos...

Induction of specific immunological unresponsiveness by feeding protein antigens is termed oral tolerance and may be a potential therapy for autoimmune diseases. Whereas oral tolerance therapy may be both simple and effective, the requirement for large amounts of protein will limit clinical testing of autoantigens, which are difficult to produce. We have previously demonstrated transgenic plant...