E4 CUTIS WWW.CUTIS.COM To the Editor: A 34-year-old woman presented for evaluation of dry mouth and painless peeling of the oral mucosa of 2 months’ duration. She denied any other skin eruptions, dry eyes, vulvar or vaginal pain, or recent hair loss. A recent antinuclear antibodies test was negative. The patient’s medical history was otherwise unremarkable and her current medications included m...

Eosinophilic ulcer of the oral mucosa is a rare, self-limiting, chronic and benign lesion of unknown pathogenesis that affects the oral mucosa. We present the case of a 65 year-old Caucasian female with a five month history of a painful ulcer on the lateral side of her tongue. The ulcer was not adhered to the underlying structures and there was no evidence of regional lymph node involvement. La...

Immunohistochemistry was used to identify, enumerate, and describe the tissue distribution of Langerhans type (CD1a and CD207), myeloid (CD1c and CD141), and plasmacytoid (CD303 and CD304) dendritic cell subsets in oral mucosa of allergic and non-allergic individuals. Allergic individuals have more CD141+ myeloid cells in epithelium and more CD1a+ Langerhans cells in the lamina propria compared...

The lip brake is a fold in the oral mucosa, originating upper and insertion alveolar mucosa. At birth, labial frenum may be inserted palatal papilla. As individual grows, he can migrate to more region, featuring normal curl. However, when it remains papilla, case of hypertrophic When pathological, this structure promote formation interincisal diastema, periodontal pocket, gingival retraction, a...

The purpose of this study was to analyze the stress and strain inside of the oral mucosa in partially-edentulous patients. The patient-specific finite element models of the mucosa and the bone were constructed using the CT images and in-vivo surface measurement during a continuous load. The mean initial shear modulus of 8.3 × 10(-5) (GPa) and the mean relaxation time of 503 (s) were determined ...

primary oral melanoma is a rare neoplasm of melanocytic origin, accounting for 0.5% of all oral malignancies. the “chameleonic” presentation of a mainly asymptomatic condition, rarity of this lesion, poor prognosis, and the necessity of a highly specialized treatment are factors that should be seriously considered by the involved health provider. here is a case report presenting a malignant mel...

PURPOSE The purpose of this study was to clarify the "healing capacity" of wounds of the oral mucosa in comparison to those of the skin, and to evaluate the wound healing mechanism of oral mucosa using a cytobiological approach from the aspect of energy metabolism in oral keratinocytes. MATERIALS AND METHODS Samples of epidermal and oral keratinocytes collected at surgery and of cultured oral...

Introduction: The inferiorly and laterally based platysma myocutaneous flap contains hair in some ethnics; therefore, it is required to change the myocutaneous flap to myofascial flap to prevent the hair growth after its transfer to the oral cavity.   Materials and Methods: Five male mongrel dogs were selected for this study. De-epithelialized laterally based platysma fl...

A case of lichen sclerosus et atrophicus (LSA) involving the oral mucosa is described. The lesion began in the labial mucosa with extension to the gingiva and to the skin. The frequency of occurrence of oral lesions of LSA is discussed, and a histopathologic comparison with skin lesions is made.

Understanding of the functional morphology and biology of the oral mucosa has advanced in recent year, particularly in such areas as epithelial-mesenchymal interaction, fibroblast heterogeneity, extracellular matrix, migration factors and growth factors, and the importance of these areas in the development and maintenance of the oral mucosa is increasingly appreciated. This article reviews curr...