Haemangiomas, the most common type of benign vascular tumours, are rare in the oral cavity. Some of these lesions are congenital and show symptoms in late childhood or early adult life. A 32-years-old woman presented with a huge lesion on her tongue which caused dysphagia and dysphasia. She had first noticed the lesion when she was 6. Her obstructive symptoms started when she was 28 and, despit...

A decrease in the almost fifty percent mortality rate from oral cancer is needed urgently. Improvements in early diagnosis and more effective preventive treatments could affect such a decrease. Towards this end, we undertook for the first time an in-depth mass spectrometry-based quantitative shotgun proteomics study of non-invasively collected oral brush biopsies. Proteins isolated from brush b...

Background: Peripheral giant cell granuloma (PGCG) or the so-called epulis is most common oral lesion. It normally appears as a soft tissue purple-red nodule. This lesion certainly not true neoplasm, but in nature, it may be reactive, thought to stimulated by local irritation trauma. Nonetheless, exact cause definitely understood well. In appearance, lesions vary from smooth, uniformly outlined...

Oral erythema multiforme presents with oral and lip ulcerations typical of erythema multiforme but without skin target lesion. The primary attack is confined to oral mucosa but subsequent attacks can produce more severe forms of erythema multiforme involving skin. It is important to distinguish it from other oral ulcerative disorders for early diagnosis and treatment. Here we report a case of o...

Intravascular papillary endothelial hyperplasia (IPEH) is an unusual reactive lesion of vascular origin, which rarely occurs in the oral cavity. Pathogenetically, is it divided into true, mixed and extra-vascular types. We report a case of extra-vascular IPEH of the lower lip in 54-year-old female patient. Patient gives history of trauma 4 months back with lesion developing at the site to traum...

A 55-year-old man presented with oral mucosal ulcers, blackening of both hands, and hyperpigmentation on axillary, anal, and inguinal regions for the last 3 months, which were all progressive. The patient was referred to the oncology department with the diagnosis of acanthosis nigricans for investigation of an underlying malignancy. He was a smoker. A computed tomography scan of thorax revealed...