BACKGROUND Oral food challenges (OFCs) are performed for diagnosis of a food allergy in cases where the allergy is not supported by patient history, or when a newly developed tolerance level needs to be established. OBJECTIVE We aimed to investigate the prevalence and severity of reactions during OFCs in preschool children. METHODS A retrospective study was conducted on children younger tha...

Background The prevalence of Food Allergy (FA) is increasing and the correct diagnosis is mandatory among patients with adverse reactions to foods. The oral food challenge tests (OFCT) remain the better tests for FA diagnosis and its usage is essential to avoid misdiagnosis. As severe reactions may occur, staff must be prepared to manage lifethreatening situations. The aim of this study was to ...

The frequency of negative hydrogen breath tests due to colonic bacterial flora which are unable to produce hydrogen was determined after oral lactulose challenge in 98 healthy Dutch schoolchildren. There was a negative result in 9.2%. The probability of a false normal lactose breath test (1:77) was calculated from these results together with those from a separate group of children with lactose ...

BACKGROUND Gestational diabetes is the second common disorder in pregnancy period, which is detected in 24-28 weeks of gestational age through screening tests in low-risk women. The women with gestational diabetes are prone to prenatal mortality and development of future diabetes. Therefore, detection of these individuals in the first trimester and conducting preventive interventions is of grea...

Gestational diabetes mellitus (GDM) is associated with a high risk of immediate and late adverse outcomes for mothers and their offspring (1–4). This risk correlates with the level ofmaternal hyperglycemia (5), and glucose-lowering interventions were reported to decrease the risk of some of these adverse outcomes (6). In many countries, including Israel, a two-step approach for GDM screening is...

Objective: To determine the frequency of gestational diabetes mellitus (GDM) among pregnant females. Study Design: Cross-sectional study. Place and Duration: Department Gynecology Obstetrics, department Pathology, Dow University health sciences, From February 2021 to January 2022. Methodology: Five hundred ladies with age between 24-28 weeks any parity were included. These women challenged 75 g...

The selective 5-hydroxytryptamine-1 receptor agonist sumatriptan inhibits exocrine pancreatic function in humans. No data are available on the effect of sumatriptan on fasting and postprandial endocrine pancreatic function in humans. To elucidate the influence of 5-hydroxytryptamine-1 receptor activation by sumatriptan on endocrine pancreatic function and blood glucose homeostasis, we determine...

OBJECTIVE To propose new cutoffs in plasma glucose levels in screening and diagnosis of gestational diabetes mellitus (GDM) in the first trimester of pregnancy. METHODS A 50-gram oral glucose challenge test (GCT) was performed in 1,716 singleton pregnancies at 6-14 weeks' gestation. In those with a positive GCT, a 100-gram glucose tolerance test (GTT) was carried out. The GCT and as necessary...

Aims: To determine effect of nifedipine on blood glucose levels through oral glucose tolerance test in normoglycemic albino Rats and magnitude of its effect on basal v/s glucose induced glycemic value. Methods: Normal adult albino rats of either sex weighing between 150 – 200g were randomly divided into 2 groups(n=6); Control(distilled water-1ml/rat) and Test(nifedipine-1.5mg/kg BW) and the res...