The hangover effects of 768 mg chlormethiazole, an hypnotic with a half-life of approximately 4 hr, were compared with those of placebo in a double-blind cross-over study in 8 young subjects. Ten hours after dosing there were no differences between the preparations in the subjects' psychomotor performance, EEG sleep scores, or visual analogue ratings. Thus, an hypnotic which is rapidly removed ...

INTRODUCTION Information regarding gender differences in drug use of adolescents is essential for designing gender-specific drug prevention policies. This study was conducted in high school students in Tehran, Iran, in 2007. Here, we report the gender differences in lifetime prevalence as well as psychosocial associates of drug use. MATERIAL AND METHODS This was a gender analysis of the data ...

Avoiding a hangover is a great goal to have! Many folks who participate in moderate or higherrisk drinking [2] experience a hangover at some point (though some people can experience a hangover with just one drink). A hangover isn't just one symptom; it's a set of possible symptoms a person may experience after consuming alcohol. With a bit of planning, symptoms of hangovers can be minimized whe...

Most anaesthetists would agree that there is room for a more satisfactory intravenous anaesthetic than thiopentone. This drug is a powerful depressor both of blood pressure and of respiration. The compound G.29.505 was investigated in the laboratory by Thuillier and Domenjoz (1957), and appeared to offer some promise, particularly because of some tendency on its part to stimulate respiration. F...

OBJECTIVE Deficits in emotion expression skills have been associated with alcohol and substance use, but the mechanisms through which these associations occur are not well understood. The current study investigated (a) associations between emotion expression and substance use (i.e., alcohol, cigarettes, and marijuana) in newly parenting adolescents and young adults and (b) whether symptoms of d...

PURPOSE Increasing evidence suggests the existence of heterogeneity in the development of depressive symptoms during adolescence, but little remains known regarding the implications of this heterogeneity for the development of commonly co-occurring problems. In this study, we derived trajectories of depressive symptoms in adolescents and examined the codevelopment of multiple behavioral and aca...

BACKGROUND We describe the prevalence of behaviors that put American Indian and Alaska Native (AI/AN) high school students at risk for teen pregnancy and sexually transmitted infections (STIs) and the relationships among race/ethnicity and these behaviors. METHODS We analyzed merged 2007 and 2009 data from the national Youth Risk Behavior Survey, a biennial, self-administered, school-based su...

Although numerous studies have established a link between substance use and adult partner violence, little research has examined the relationship during adolescence and most extant research has not examined multiple substance use types. The current study used hierarchical growth modeling to simultaneously examine proximal (between-person) and time-varying (within-person) relations between cigar...

Drunk-dialing is a term documented in both popular culture and academic literatures to describe a behavior in which a person contacts another individual by phone while intoxicated. In our collective clinical experience we have found that clients drunk-dial their clinicians too, particularly while in substance use treatment, and yet there is a noticeable absence of research on the topic to guide...

This article examines taste clusters of musical preferences and substance use among adolescents and young adults. Three analytic levels are considered: fixed effects analyses of aggregate listening patterns and substance use in US radio markets, logistic regressions of individual genre preferences and drug use from a nationally representative survey of US youth, and arrest and seizure data from...