Addiction is a major problem of society. The existing evidences have shown that parental addiction impairs CNS development, learning, and memory. With respect to the role of glutamate in dentate gyrus on learning and memory, in this study, the effect of parental addiction to morphine on extracellular glutamate concentration in dentate gyrus was evaluated. For this purpose, male and female rats ...

aim: the purpose of this study was to compare the attention bias about tempting incentives related to opium materials in treated, addicted and normal people. duration of consumption and treating were also considered. method: in this causal-comparative study population was all addicted people who were referred to the rehabilitation offices, addiction treatment clinic, rebirthing centers and narc...

Background: Emotion regulation appears to provide individuals with a doubled ability to avoid drug relapse and assists with the control of temptation to reuse, which is a type of tendency-avoidance conflict. The present study aims to investigate the effect of Gross model-based emotion regulation training on the reduction of craving beliefs in drug-addicted people.Methods: The present study was ...

Editorial of vol. 29-4.

In this issue of Blood, Willems et al describe the dependence of acute myeloid leukemia (AML) cells on glutamine for maintaining protein synthesis downstream of mammalian target of rapamycin (mTOR) and show that the enzyme asparaginase can be used to target this dependence. Using various AML cell lines, primary samples, and CD341 stem cells from healthy donors, the authors support the notion th...

Modern imaging techniques enable researchers to observe drug actions and consequences as they occur and persist in the brains of abusing and addicted individuals. This article presents the five most commonly used techniques, explains how each produces images, and describes how researchers interpret them. The authors give examples of key findings illustrating how each technique has extended and ...

Aims Despite alcohol being the most often used addictive substance among addicted patients, use of other substances such as cocaine has increased over recent years, and the combination of both drugs aggravates health impairment and complicates clinical assessment. The aim of this study is to identify and characterize heterogeneous subgroups of cocaine- and alcohol-addicted patients with common ...

the widespread use of internet has caused new psychological, social, and educational problems for the students. the aim of this study was to examine the quality of life in medical students who suffer from internet addiction. this cross-sectional survey was carried out in tehran university of medical sciences, and a total of 174 fourth-to seventh-year undergraduate medical students were enrolled...

background: opium is one of the most commonly abused opiates in developing countries including iran. considering the importance of maternal health on the newborn, we aimed to assess the effect of opium abuse on fetal heart rate (fhr) characteristics in a sample of pregnant women in zahedan, southeast iran. methods: this cross-sectional study was done on 100 pregnant women referring to ali-ibn-a...

conclusions dexmedetomidine added to bupivacaine in spinal anesthesia is more effective to increase duration of block, providing more appropriate sedation and less postoperative pain scale and post-operative nausea and vomiting (ponv) compared to fentanyl additive. results totally, 84 patients were randomly divided into three groups of 28 patients. onset of sensory block in dex group was signif...