domperidone is a widely used antiemetic, poorly water soluble drug, erratically absorbed in stomach and possess several dissolution-related problems thus it has poor bioavailability. solubility of a drug plays a very important role in dissolution and hence absorption of drug which ultimately affects its bioavailability. hence, by considering the facts related to drug, attempts have been made to...

A series of heterobinuclear, thiocyanato-bridged complexes of cations [M(NH2X)6 ] 2+, and [M(en)3 ] 2+ (where X = H, Ph; M=Cu, Co, Cd, Zn) with anion [Ni(NCS)4 ] 2 –have been prepared by 1:1 molar ratio. The complexes have been characterized by FT-IR, 13C NMR and UV-vis spectroscopy, metal analysis, magnetic and conductance studies. The complexes have the following composition: [M(NH2 X)5 ][Ni(...

the forumad ophiolite in the northwestern part of the sabzevar region has embraced the largedepleted harzburgites and dunitic bodies associated with podiform chromitites. in some deposits, chromitegrains have segregated as nodules. the stretched shape along with high cr2o3 and tio2 contents are thecharacteristics of the nodules. compared to the other tethyan nodular chromites, the forumad nodul...

in this paper, two double helical dinuclear copper(ii) complexes of bis-n,o-bidentate schiff base ligands bis(3-methoxy-n-salicylidene-4,4'-diaminodiphenyl)sulfone (l1) and bis(5-bromo-n-salicylidene-4,4'-diaminodiphenyl)sulfone (l2) were prepared and characterized by elemental analyses (chn), as well as thermal analysis. elemental analyses (chn) suggested that the reaction between ligands and ...

Stabilities and quantum molecular descriptors of cyclophoshphamide (an anticancer drug)-functionalized (8,0) zigzag and (4,4) armchair carbon nanotubes (CNTs) complexes in water were studied using density functional theory (DFT) calculations. Two attachments namely the sidewall- and tip-attachments are considered for the model constructions. Calculations of the total electronic energy (Et) and ...

A new series of transition metal complexes of Co(II), Ni(II), Cu(II) and Zn(II), has beensynthesized from the Knoevenagel condensate Schiff base ligand(L) derived from β-ketoanilideand furfural with o-phenylenediamine and diethylmalonate. Structural features were determinedby spectral and analytical techniques. Square-planar geometry has been adopted by thecomplexes except cobalt complex which ...

Recognition of fundamental tectonic boundaries has been extremely difficult in the (>1000-km-wide) Proterozoic accretionary orogen southwestern North America, where main rock types are similar over large areas, and region experienced multiple postaccretionary deformation events. Discrete ultramafic bodies present a number areas that may mark important boundaries, especially if they can b...

Subduction initiation processes, such as those evidenced in the Izu-Bonin-Mariana (IBM) forearc crust are a key feature of modern-style plate tectonics. However, evidence for this process Precambrian is limited, due to scarcity ophiolite suites and particular lack typical complete ophiolitic sequences similar observed Phanerozoic ophiolites. Mineral analyses olivine, orthopyroxene, chrome spine...