نتایج جستجو برای: operational tau method

تعداد نتایج: 1713779  

1982
John A. Jaros

2. Method. Tau leptons are pair-produced in e+eannihilations, so each tau has the known beam energy. Thus we can measure the lifetime by determining the average decay length of the taus; at PEP energies, Ec, =29 GeV, it is expected to be about 700 p. The decay length can be measured when the tau decays in the three-chargedprong topology. It is simply the distance between the production point, i...

Journal: :Biophysical journal 2005
Alvaro Sanchez-Andres Yan Chen Joachim D Müller

Mandel's Q-parameter, which is determined from the first two photon count moments, provides an alternative to PCH analysis for determining the brightness of fluorophores. Here, the definition of the Q-parameter is generalized to include correlations between photon counts that are separated by a time tau. We develop and experimentally verify a theory that takes the effects of dead time, afterpul...

2017
Sima Seifabadi Golnaz Vaseghi Shaghayegh Haghjooy Javanmard Elham Omidi Mohammadhasan Tajadini Bahareh Zarrin

OBJECTIVES Breast cancer is an important leading cause of death from cancer. Stathmin and tau proteins are regulators of cell motility, and their overexpression is associated with the progression and bad prognosis of breast cancer. Memantine, an N-methyl-D-aspartate (NMDA) receptor antagonist, is the potential inhibitor of tau protein in neurons. This study determines the effect of memantine on...

Journal: :Journal of neuropathology and experimental neurology 2015
Elizabeta B Mukaetova-Ladinska Zeinab Abdel-All Estibaliz Santiago Mugica Mosi Li Lucy J L Craggs Arthur E Oakley William G Honer Raj N Kalaria

We previously reported that, in the brains of older patients with vascular dementia (VaD), there is a distinctive accumulation of detergent-extractable soluble amyloid-β, with a predominance of Aβ42 species. It is unclear, however, if tau proteins also accumulate in the brains of older VaD subjects. Using antibody-specific immunoassays, we assessed concentrations of total tau (t-tau) and phosph...

2009
DAVID F. ANDERSON ARNAB GANGULY THOMAS G. KURTZ

We perform an error analysis for numerical approximation methods of continuous time Markov chain models commonly found in the chemistry and biochemistry literature. The motivation for the analysis is to be able to compare the accuracy of different approximation methods and, specifically, Euler tau-leaping and midpoint tau-leaping. We perform our analysis under a scaling in which the size of the...

2003
Suzan Edwards William Fischer John Kwan Lynne Hillenbrand A. K. Dupree

He i l10830 profiles acquired with Keck’s NIRSPEC for six young low-mass stars with high disk accretion rates (AS 353A, DG Tau, DL Tau, DR Tau, HL Tau, and SVS 13) provide new insight into accretion-driven winds. In four of the stars, the profiles have the signature of resonance scattering, and they possess a deep and broad blueshifted absorption that penetrates more than 50% into the 1 mm cont...

2017
Takashi Kasai Harutsugu Tatebe Masaki Kondo Ryotaro Ishii Takuma Ohmichi Wing Tung Esther Yeung Masafumi Morimoto Tomohiro Chiyonobu Naoto Terada David Allsop Masanori Nakagawa Toshiki Mizuno Takahiko Tokuda

Down syndrome (DS) is the most prevalent chromosomal abnormality. Early-onset dementia with the pathology of Alzheimer's disease (AD) frequently develops in DS. Reliable blood biomarkers are needed to support the diagnosis for dementia in DS, since positron emission tomography or cerebrospinal fluid sampling is burdensome, particularly for patients with DS. Plasma t-tau is one of the establishe...

Journal: :Computational & Applied Mathematics 2023

This paper is concerned with the numerical solution of Volterra integral equations third kind non-smooth solutions based on recursive approach spectral Tau method. To this end, a new set fractional version canonical basis polynomials (called FC-polynomials) introduced. The approximate polynomial Tau-solution) expressed in terms FC-polynomials. structure Tau-solution allows recovering standard d...

Journal: :Journal of Alzheimer's disease : JAD 2015
Erika J Starks J Patrick O'Grady Siobhan M Hoscheidt Annie M Racine Cynthia M Carlsson Henrik Zetterberg Kaj Blennow Ozioma C Okonkwo Luigi Puglielli Sanjay Asthana N Maritza Dowling Carey E Gleason Rozalyn M Anderson Nancy J Davenport-Sis LeAnn M DeRungs Mark A Sager Sterling C Johnson Barbara B Bendlin

BACKGROUND Insulin resistance (IR) is linked with the occurrence of pathological features observed in Alzheimer's disease (AD), including neurofibrillary tangles and amyloid plaques. However, the extent to which IR is associated with AD pathology in the cognitively asymptomatic stages of preclinical AD remains unclear. OBJECTIVE To determine the extent to which IR is linked with amyloid and t...

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