Aim—frailty is an emerging concept in primary care, which potentially can provide healthcare commissioners with a clinical focus for targeting resources at an ageing population. However, primary care practitioners need valid instruments that are easy to use. With that purpose in mind, we created a Frailty Instrument (FIt) for primary care based on the Survey of Health, Ageing and Retirement in ...

• The accuracy of a binary diagnostic test can easily be assessed by comparing the sensitivity and specificity with the status of respondents. When the result of a diagnostic test is continuous, the assessment of accuracy depends on a specified threshold. The receiver operating characteristic (ROC) curve, which includes all possible combinations of sensitivity and specificity, provides an appro...

BACKGROUND No clear consensus has been reached yet on how best to characterize children who suffer from pediatric bipolar disorder (PBD). The CBCL-PBD profile on the Child Behavior Checklist (CBCL) has been consistently reported showing deviant findings on the Attention Problems, Aggressive Behavior, and Anxious-Depressed subscales. AIM To examine the sensitivity and specificity of the propos...

A representation and interpretation of the area under a receiver operating characteristic (ROC) curve obtained by the "rating" method, or by mathematical predictions based on patient characteristics, is presented. It is shown that in such a setting the area represents the probability that a randomly chosen diseased subject is (correctly) rated or ranked with greater suspicion than a randomly ch...

This review provides the basic principle and rational for ROC analysis of rating and continuous diagnostic test results versus a gold standard. Derived indexes of accuracy, in particular area under the curve (AUC) has a meaningful interpretation for disease classification from healthy subjects. The methods of estimate of AUC and its testing in single diagnostic test and also comparative studies...

The summary receiver operating characteristic (SROC) curve has been recommended to represent the performance of a diagnostic test, based on data from a meta-analysis. However, little is known about the basic properties of the SROC curve or its estimate. In this paper, the position of the SROC curve is characterized in terms of the overall diagnostic odds ratio and the magnitude of inter-study h...

Introduction: The possibility of depression is common in the elderly. Novel technologies allow us to monitor people related to depression. Hence, a model was provided to detect depression in elderly based on artificial neural network (ANN). Methods: The present study is an applied descriptive-survey research. Forty elderly people were randomly selected from the Elderly Care Center in Gonbad Ka...

Regression models are introduced into the receiver operating characteristic (ROC) analysis to accommodate effects of covariates, such as genes. If many covariates are available, the variable selection issue arises. The traditional induced methodology separately models outcomes of diseased and nondiseased groups; thus, separate application of variable selections to two models will bring barriers...

In the field of diagnostic test studies, the accuracy of a diagnostic test is essential in evaluating the performance of the test. The receiver operating characteristic (ROC ) curve and the area under the curve (AUC ) are widely used in such evaluation procedures. Meanwhile, the Youden index is also introduced into practice to measure the accuracy of the diagnostic test from another aspect. The...

Objectives: The aim of this retrospective study was to clarify whether plasma markers that are routinely used in the workup of patients suspected for acute appendicitis (AA) can stratify for imaging in both adults and children. Methods: A total of 1388 patients suspected of AA between January 2008 and till 2012 were included. CRP and WBC concentrations were retrospectively abstracted from the e...