OBJECTIVE To evaluate the effect of a 3-month course of GnRH agonist administered immediately before IVF-ET in infertile patients with endometriosis. DESIGN Prospective, randomized trial. SETTING Three tertiary care assisted reproductive technology programs. PATIENT(S) IVF-ET candidates with surgically confirmed endometriosis. INTERVENTION(S) Twenty-five patients received three courses ...

BACKGROUND LH activity may influence treatment response and outcome in IVF cycles. METHODS A randomized, assessor-blind, multinational trial compared ongoing pregnancy rates (primary end-point) in 731 women undergoing IVF after stimulation with highly purified menotrophin (HP-hMG) (n = 363) or recombinant FSH (rFSH) (n = 368) following a long GnRH agonist protocol. Patients received identical...

The aim of this study was to create reliable models to predict the probability of achieving an ongoing pregnancy during in-vitro fertilization (IVF) treatment: model A, at the start of the first treatment, model B at the time of embryo transfer, and model C, during the second treatment at the end of the first IVF treatment. Prognostic models were created using data from the University Hospital ...

Abstract Study question Is there an association between mitochondrial DNA (mtDNA) content and Ongoing Pregnancy Rate (OPR) in D5 or D6 euploid blastocyst? Summary answer Day6 OPR is decreased high mtDNA blastocyst. Day5 levels are independent of maternal age standard morphology. What known already Preimplantation development energy-demanding process ATP production crucial for cellular activity ...

Abstract Study question Do embryos with early blastulation (EB) on D4 show higher implantation potential compared to top D5 blastocysts in fresh elective single embryo transfer (eSET) cycles? Summary answer Fresh EB time start (tSB)<96.6h and of expanded blastocyst (tEB)<100h post-insemination is predictive ongoing pregnancy for patients <35. What known already Expansion ha...