نتایج جستجو برای: onchocerca volvulus
تعداد نتایج: 3233 فیلتر نتایج به سال:
The absence of animal models in which to reproduce successfully the complete life cycle of Onchocerca volvulus has hindered progress towards unravelling the processes involved in the regulation of parasite abundance in the vertebrate host. Mathematical frameworks have been developed to explore the consequences of such processes in determining parasite population dynamics and the effect on these...
BACKGROUND Community Directed Treatment with ivermectin is the cornerstone of current efforts to eliminate onchocerciasis. However recent studies suggest there are foci where long-term annual distribution of the drug alone has failed to ensure elimination thresholds are reached. It is important to achieve high levels of compliance in order to obtain elimination targets. An epidemiological and e...
We consider an ideal gas of massive hadrons in thermal and chemical equilibrium. The gas expands longitudinally in an adiabatic way. This evolution for a baryonless gas reduces to a hydrodynamic expansion. Cooling process is parametrized by the sound velocity. The sound velocity is temperature dependent and is strongly influenced by hadron mass spectrum. ∗Work partially supported by the Polish ...
On Monday December 21, 2015, an information session was organized by the Ugandan Health minister Dr Elioda Tumwesigye in Pader district, northern Uganda, to explain the results of the investigations performed in Uganda to identify the cause of nodding syndrome (NS). NS was first reported in Uganda in the districts of Kitgum, Pader, and Lamwo in 2009. Retrospective studies would suggest cases as...
BACKGROUND Observations were made on the prevalence of onchocerciasis and Onchocercal Skin Diseases (OSD); frequency of occurrence and anatomical distribution of OSD in the Hawal River Valley, an established onchocerciasis endemic focus in north-eastern Nigeria. METHODS Symptoms of OSD were diagnosed in 5 844 subjects using Rapid Assessment Method (RAM) while 1 479 of the subjects chosen from...
BACKGROUND Recently, several epidemiological studies performed in Onchocerca volvulus-endemic regions have suggested that onchocerciasis-associated epilepsy (OAE) may constitute an important but neglected public health problem in many countries where onchocerciasis is still endemic. MAIN TEXT On October 12-14th 2017, the first international workshop on onchocerciasis-associated epilepsy (OAE)...
Complete cDNA and genomic sequences encoding the Onchocerca volvulus S-adenosylmethionine decarboxylase (SAMDC), a key enzyme in polyamine biosynthesis, have been isolated and characterized. The deduced amino acid sequence encodes a 42 kDa proenzyme with a moderate level of sequence homology to eukaryotic SAMDCs. Enzymically active O. volvulus SAMDC was expressed at a high level in an Escherich...
Onchocerciasis, caused by the filarial nematode Onchocerca volvulus, is a parasitic disease leading to debilitating skin disease and blindness, with major economic and social consequences. The pathology of onchocerciasis is principally considered to be a consequence of long-standing host inflammatory responses. In onchocerciasis a subcutaneous nodule is formed around the female worms, the core ...
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