The aim of the present study was to investigate Ki67 expression level and measure cell proliferation index (Ki67) in odontogenic benign tumors. This an analytical cross-sectional sampling non-probabilistic with exhaustive recruitment including all biopsy or surgical excision specimen immunohistochemistry performed on histological sections paraffin-fixed tissues 3µ thickness (MM1) monoclonal ant...

background: cyclo-oxygenase-2 (cox-2) is an early response gene that is induced by growth factors, oncogenes and carcinogens and its expression is increased in various tumors. increased expression of cox-2 plays a signifi cant role in the development and growth of tumors by interfering in biological processes such as cell division, cellular immunity, cell adhesion, apoptosis, and angiogenesis. ...

Ameloblastoma is characteristically considered to be a benign but locally aggressive and infiltrative odontogenic tumor with high recurrence rate. Because of its invasive nature, the rates for ameloblastoma post treatment remains high. Recurrence also seems depend on histological type modalities used. Curettage alone reported have led 90% rate mandibular tumors 100% maxillary in literature. In ...

BACKGROUND Keratocystic odontogenic tumors (KCOTSs) are odontogenic tumors previously referred to as odontogenic keratocysts. Several studies have reported that KCOT behavior is more like that of a benign neoplasm than a cyst. KCOTs are locally destructive and exhibit a high recurrence rate. The objective of this study is to characterize the expression of p53, p63 and p73 in KCOTs together with...

Considerable variation in the clinicopathologic presentation of epithelial odontogenic tumors can sometimes be confusing and increase the chance of misdiagnosis. Seven diagnostically challenging jawbone lesions are described. There were 2 cases of mistaken identity in our ameloblastoma file. One unicystic type, initially diagnosed and treated as a lateral periodontal cyst, showed destructive re...

BACKGROUND CD166 is a glycoprotein of an immunoglobulin super family of adhesion molecules that has been associated with aggressive characteristics and high recurrence rate of tumors. Different odontogenic lesions exhibit considerable histological variation and different clinical behavior. In an attempt to clarify the mechanisms underlying this different behavior, the present study investigates...