BACKGROUND Wnt/β-catenin signaling pathway is essential for the beginning of odontogenesis and may be involved in the development and progression of some odontogenic tumors. Thus, the aim of this study was to comparatively evaluate the immunohistochemical expression of Wnt/β-catenin signaling pathway proteins in a series of AME and CCOT. MATERIAL AND METHODS Immunohistochemical reactions were...

LIM-homeobox containing (Lhx) genes encode trascriptional regulators which play critical roles in a variety of developmental processes. We have identified two genes belonging to a novel subfamily of mammalian Lhx genes, designated Lhx6 and Lhx7. Whole-mount in situ hybridisation showed that Lhx6 and Lhx7 were expressed during mouse embryogenesis in overlapping domains of the first branchial arc...

Desmoplastic ameloblastoma is a rare variant of benign odontogenic tumors. Our objective was to describe the clinical and pathological features of desmoplastic ameloblastoma. Three cases of desmoplastic ameloblastoma that were treated in the authors’ department were reviewed and analyzed along with radiological and histological data. The findings obtained from pathological examinations of two s...

AIM To investigate the expression of CD56 in dog odontogenesis in order to elucidate the expression found in ameloblastomas. MATERIALS AND METHODS Immunohistochemical analysis of CD56 expression of developing dog teeth in the bud, cap and bell stages including the remnants of the dental lamina. RESULTS Weak CD56 expression was observed in the dental epithelium during the bud stage with inte...

background: pericoronal tissue is the soft tissue located between the bony crypt and the impacted tooth, which is histologically composed of fi brous connective tissue and is usually lined by the reduced enamel epithelium. increased epithelial cell proliferation in the pericoronal tissue is associated with pathological changes such as development of an odontogenic cyst or an epithelial odontoge...

A dentigerous cyst is a benign lesion arising from the odontogenic epithelium associated with crown of an impacted tooth. They are radiolucent and unilocular, usually asymptomatic diagnosed in clinical routine or radiographic examinations. The lower third molars upper canines most affected teeth, also odontomas supernumerary teeth. slow-growing but can reach considerable dimensions, causing fac...

Nasolabial cyst is a rare, non-odontogenic that occurs in the submucosa of anterior nasal floor. Its most likely origin known to be remnants nasolacrimal duct. The patient usually comes hospital for swelling or pain nasolabial area, and diagnosis made by combining clinical features, radiologic imaging, histological test. commonly used treatment surgical excision via sublabial approach. A 40-yea...

We report two cases of peripheral odontogenic fibroma the maxillary anterior gingiva. The first patient was a 46-year-old woman with three-year history painless mass near left lateral incisor tooth. Intraoral examination revealed firm nodule smooth surface. CT images showed radiolucent lesion consistent mass. second 41-year-old who had been aware an asymptomatic hemorrhagic situated in midline ...

Background: Ameloblastic carcinoma is a rare and malignant odontogenic tumour possibly arising de-novo from pre-existing ameloblastoma. It aggressive locally destructive. Ameloblastoma the most common benign of mandible. originates tooth-forming epithelium, where its aetiology remains unknown. usually grows slowly, asymptomatic, destroys surrounding bone tissue. Malignant transformation amelobl...

AIM To report a case of a non-neoplastic variant of calcifying odontogenic cyst (COC) with the lining epithelium showing ameloblastomatous proliferation and capsule exhibiting features of a cholesterol granuloma. The importance of delineating this histologic variant from unicystic ameloblastoma and the formation of cholesterol granuloma in this variant is discussed. BACKGROUND Calcifying odon...