Abstract Robot manipulators perform a point-point task under kinematic and dynamic constraints. Due to multi-degree-of-freedom coupling characteristics, it is difficult find better desired trajectory. In this paper, multi-objective trajectory planning approach based on an improved elitist non-dominated sorting genetic algorithm (INSGA-II) proposed. Trajectory function planned with new composite...

Type 2 diabetes (T2D) exists in 25-40% of hospitalized patients. Therapeutic inertia is the delay in the intensification of a treatment and it is frequent in T2D. The objectives of this study were to detect patients admitted to surgical wards with hyperglycaemia (HH; fasting glycaemia > 140 mg/dL) as well as those with T2D and suboptimal chronic glycaemic control (SCGC) and to assess the midter...

Researchers have attempted to improve the quality of clustering solutions through various mechanisms. A promising new approach to improve clustering quality is to combine data from multiple related datasets (tasks) and apply multi-task clustering. In this paper, we present a novel framework that can simultaneously cluster multiple tasks through balanced Intra-Task (within-task) and Inter-Task (...

Nonsteroidal anti-inflammatory drugs (NSAIDs) are the drugs most frequently involved in hypersensitivity reactions. These reactions include various clinical entities with different mechanisms leading to the release of inflammatory mediators. Characterization of patients based on clinical manifestations and suspected underlying mechanisms is critical for implementation of adequate diagnostic pro...

BACKGROUND Antiretroviral medicines (ARVs) are one of the most costly parts of HIV/AIDS treatment. Many countries are struggling to provide universal access to ARVs for all people living with HIV and AIDS. Although substantial price reductions of ARVs have occurred, especially between 2002 and 2008, achieving sustainable access for the next several decades remains a major challenge for most low...

Abstract Single-objective continuous optimization can be challenging, especially when dealing with multimodal problems. This work sheds light on the effects that multi-objective may have in single-objective space. For this purpose, we examine inner mechanisms of recently developed sophisticated local search procedure SOMOGSA. method solves problems based first expanding problem an additional ob...

The major objectives of this work are to estimate the hypertension (HT) frequency in the east of Morocco and to study the relationship between HT, type 2 diabetes and obesity. Our sample is composed of 1628 adults aged 40 years and older, recruited voluntarily by using the convenience sampling method through 26 screening campaigns in urban and rural areas of the east of Morocco. We enumerated 5...

BACKGROUND Despite the favorable effects of behavior change interventions on diabetes risk, lifestyle modification is a complicated process. In this study we therefore investigated opportunities for refining a lifestyle intervention for type 2 diabetes prevention, based on participant perceptions of behavior change progress. METHODS A 30 month intervention was performed in Dutch primary care ...