نتایج جستجو برای: nucleotide polymorphism

تعداد نتایج: 201089  

Journal: :مجله پزشکی مولکولی 0
marzieh asadi endocrinology and metabolism research center, arak university of medical sciences, arak, iran. abdolrahim sadeghi endocrinology and metabolism research center, arak university of medical sciences, arak, iran. mohammad reza rezvanfar endocrinology and metabolism research center, arak university of medical sciences, arak, iran. afsaneh talaie endocrinology and metabolism research center, arak university of medical sciences, arak, iran. fatemeh rafiei endocrinology and metabolism research center, arak university of medical sciences, arak, iran.

introduction: gestational diabetes mellitus (gdm) is defined as abnormal glucose tolerance that is first identified or diagnosedduring pregnancy.deiodinase d2 is essential for the local production of t3 through deiodination of triiodothyroxine (t4). several polymorphisms in d2 have been described. the single-nucleotide polymorphism (snp) in d2 thr92ala is associated with decreased enzyme activi...

Journal: :Journal of lipid research 1989
S G Young S T Hubl

An apolipoprotein (apo) B-specific monoclonal antibody, MB19, detects a commonly occurring two-allele genetic polymorphism in human apoB (Young, S. G., S. J. Bertics, L. K. Curtiss, D. C. Casal, and J. L. Witztum. 1986. Proc. Natl. Acad. Sci. USA. 83: 1101-1105). Antibody MB19 binds to two different allotypes of apoB, MB19(1) and MB19(2), with high and low affinity, respectively. The epitope fo...

2016
Glendon J Parker Tami Leppert Deon S Anex Jonathan K Hilmer Nori Matsunami Lisa Baird Jeffery Stevens Krishna Parsawar Blythe P Durbin-Johnson David M Rocke Chad Nelson Daniel J Fairbanks Andrew S Wilson Robert H Rice Scott R Woodward Brian Bothner Bradley R Hart Mark Leppert

Human identification from biological material is largely dependent on the ability to characterize genetic polymorphisms in DNA. Unfortunately, DNA can degrade in the environment, sometimes below the level at which it can be amplified by PCR. Protein however is chemically more robust than DNA and can persist for longer periods. Protein also contains genetic variation in the form of single amino ...

Journal: :Biodiversitas 2023

Abstract. Hatta ANNL, Sukma D, Maskromo I, Sudarsono S. 2023. Validated SNAP markers based on the CYP P450 87 A3 gene in coconut (Cocos nucifera) are associated with yearly stem height increase. Biodiversitas 24: 2503-2512. Tall and dwarf coconuts types used worldwide as parents hybrid production, they differ their height. The of is estimated 11 leaf scars length. essential stem-height increase...

Journal: :Molecular biology and evolution 2000
O Savolainen C H Langley B P Lazzaro H Fr

Nucleotide variation at the alcohol dehydrogenase locus (Adh) was studied in the outcrossing Arabidopsis lyrata, a close relative of the selfing Arabidopsis thaliana. Overall, estimated nucleotide diversity in the North American ssp. lyrata and two European ssp. petraea populations was 0.0038, lower than the corresponding specieswide estimate for A. thaliana at the same set of nucleotide sites....

Journal: :مجله پزشکی مولکولی 0
marzie asadi endocrinology and metabolism research center, arak university of medical sciences abdorahim sadeghi endocrinology and metabolism research center, arak university of medical sciences mahshid shahverdi endocrinology and metabolism research center, arak university of medical sciences afsaneh talaie endocrinology and metabolism research center, arak university of medical sciences mohammad reza rezvanfar endocrinology and metabolism research center, arak university of medical sciences fatemeh rafiei endocrinology and metabolism research center, arak university of medical sciences

introduction: a thyroid nodule is a palpable swelling in a thyroid gland with an otherwise normal appearance. palpable thyroid nodules occur in 4 to 7 percent of the population. nodular thyroid diseases are more frequent in women than in men. most actions of thyroid hormone are mediated by the active form of thyroid hormone. d2 is essential for formation of active hormone of t3 through deiodina...

Journal: : 2023

Aim. To follow the distribution and evolution of macaques genus-specific Alu repeat AluMacYa3 in Cercopithecidae MGMT gene orthologs. Methods. The homology between nucleotide sequences has been determined by BLAST 2.6.1 program. results search identification MGE have obtained CENSOR Results. It shown on example orthologs that is present not only intron macaques, but also other representatives O...

پایان نامه :دانشگاه تربیت معلم - تهران - دانشکده علوم 1393

زمینه : سنگ کلیه یک بیماری چند عاملی شایع در بین جوامع است. در بین کشورهای منطقه، ایران بالاترین آمار بین المللی شیوع سنگ کلیه را داراست . عوامل ژنتیکی و محیطی هر دو در بروز سنگ کلیه تاثیر گذارند. چندشکلی های تک نوکلئوتیدی به عنوان یکی از عوامل فیزیولوژیک موثر در بیماری سنگ کلیه شناخته شده اند. هدف این مطالعه بررسی ارتباط پلیمرفیسمrs 4065ژن اوروکینازو هم چنین پلیمرفیسم rs 548808ژن اینترلوکین ??...

Journal: :Genetics and molecular research : GMR 2010
T Tencomnao V Thongrakard W Phuchana T Sritharathikhun S Suttirat

Several lines of evidence suggest a molecular role of -1438A/G single nucleotide polymorphism in the 5-HTR2A gene promoter (rs6311) in regulating the expression of this gene, making rs6311 polymorphism a promising candidate for an association study. We looked for a possible association between rs6311 polymorphism and major depressive disorder (MDD) in a northeastern Thai population. We included...

Journal: :Genetics and molecular research : GMR 2015
Q Y Chen N Liu J Ma Y Fang Y Cao H Li Y C Liu

Clinical and experimental data have demonstrated that genetic factors play an important role in determining the susceptibility to ischemic stroke (IS). The present study was performed to clarify the association between the pre-microRNA-149 (miR-149) single nucleotide polymorphism rs71428439 and the risk of IS in the Jiangsu Han population. Polymerase chain reaction and restriction fragment leng...

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