نتایج جستجو برای: nucleic acid amplification techniques naat

تعداد نتایج: 1401179  

Journal: :Journal of clinical microbiology 2008
S M Owen C Yang T Spira C Y Ou C P Pau B S Parekh D Candal D Kuehl M S Kennedy D Rudolph W Luo N Delatorre S Masciotra M L Kalish F Cowart T Barnett R Lal J S McDougal

Serodiagnosis of human immunodeficiency virus (HIV) infection in the United States has traditionally relied on a sequential two-test algorithm: an initial screen with an enzyme immunoassay (EIA) and reflex testing of EIA-reactive specimens with a more specific supplemental test such as Western blotting or immunofluorescence. The supplemental tests are tedious, subjective, and expensive. In addi...

2014
Sanchita Bhadra Andrew D. Ellington

Nucleic acid circuits are finding increasing real-life applications in diagnostics and synthetic biology. Although DNA has been the main operator in most nucleic acid circuits, transcriptionally produced RNA circuits could provide powerful alternatives for reagent production and their use in cells. Towards these goals, we have implemented a particular nucleic acid circuit, catalytic hairpin ass...

2016
Kristina Roskos Angelika Niemz Jim Sterling

of the Dissertation Device Engineering for Infectious Disease Diagnosis using Isothermal DNA Amplification and Lateral Flow Detection By Kristina Roskos Keck Graduate Institute of Applied Life Sciences: 2013 Technologies that enable infectious diseases diagnosis in low-resource settings could greatly facilitate effective treatment and containment of such diseases. Nucleic acid amplification tes...

Journal: :Diagnostic microbiology and infectious disease 2016
Kevin E Eboigbodin Mirko Brummer Tuomas Ojalehto Mark Hoser

Zika virus has only recently gained attention due to recent large outbreaks worldwide. An easy to use nucleic acid amplification test could play an important role in the early detection of the infection and patient management. Here, we report a rapid and robust isothermal nucleic acid amplification assay for the detection of Zika virus. The method is cost-effective and compatible with portable ...

Journal: :BioTechniques 2015
Nathan A Tanner Yinhua Zhang Thomas C Evans

Nucleic acid amplification is the basis for many molecular diagnostic assays. In these cases, the amplification product must be detected and analyzed, typically requiring extended workflow time, sophisticated equipment, or both. Here we present a novel method of amplification detection that harnesses the pH change resulting from amplification reactions performed with minimal buffering capacity....

Journal: :Nucleic acids research 2001
G Nallur C Luo L Fang S Cooley V Dave J Lambert K Kukanskis S Kingsmore R Lasken B Schweitzer

While microarrays hold considerable promise in large-scale biology on account of their massively parallel analytical nature, there is a need for compatible signal amplification procedures to increase sensitivity without loss of multiplexing. Rolling circle amplification (RCA) is a molecular amplification method with the unique property of product localization. This report describes the applicat...

Journal: :Frontiers in Bioengineering and Biotechnology 2015

Journal: :Advanced Techniques in Biology & Medicine 2017

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