نتایج جستجو برای: ns3 helicase
تعداد نتایج: 10524 فیلتر نتایج به سال:
Introduction: Dendritic cells (DCs) have been recently employed as carriers for vaccines against several viral infections. The present study was designed to develop a prophylactic vaccine against hepatitis C virus (HCV) using DCs treated with Berberis vulgaris root extract (BRE), as a preclinical study. Methods: BRE was prepared and injected to female BALB/c mice for DCs expansion. The expanded...
Introduction: Hepatitis C virus (HCV) is one of the major medical problems. Human and chimpanzees are the only specific hosts which are naturally susceptible to HCV infection. Mice and other common laboratory animals are resistant to the virus, hence HCV prophylactic and therapeutic researches are very difficult and challenging. HCV non-structural protein 3 (NS3) is one of the most attractive t...
Introduction: Dengue fever (DF) and dengue hemorrhagic (DHF) are infectious diseases caused by virus (DENV) with high mortality rates. The mainstay of treatment for DENV infection is supportive, since there were no commercial specific antiviral drug DENV. Propyl gallate has potential to be an antivirus However, the mechanism still unknown. This study aims identify activity propyl in DENV-2 repl...
BACKGROUND Translation initiation factor 4A (elF4A) is the prototype of the DEAD-box family of proteins. DEAD-box proteins are involved in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. Energy from ATP hydrolysis is used to perform RNA unwinding during initiation of mRNA translation. The presence of elF4A is required for the 43S preinitiation comple...
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