The flesh-eating bacterium group A Streptococcus (GAS) binds and activates human plasminogen, promoting invasive disease. Streptococcal surface enolase (SEN), a glycolytic pathway enzyme, is an identified plasminogen receptor of GAS. Here we used mass spectrometry (MS) to confirm that GAS SEN is octameric, thereby validating in silico modeling based on the crystal structure of Streptococcus pne...

Reseña a Carrasco Serrano, Gregorio (coord.), Economía romana en Castilla-La Mancha, Cuenca, Servicio de Publicaciones la Universidad 2020, 435 pp.

Journal of Futures MarketsVolume 43, Issue 4 p. 435-435 ISSUE INFORMATIONFree Access Markets: Volume Number 4, April 2023 First published: 06 March https://doi.org/10.1002/fut.22349AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text full-text accessPlease review our Terms and Conditions Use check box below share version article.I h...

Three new resveratrol derivatives, namely, resveratrodehydes A-C (1-3), were isolated from the mangrove endophytic fungus Alternaria sp. R6. The structures of these compounds were elucidated by analysis of their MS, 1D and 2D NMR spectroscopic data. All compounds showed broad-spectrum inhibitory activities against three human cancer cell lines including human breast MDA-MB-435, human liver HepG...

(60) Provisional application No. 60/788,859, filed on Apr. (75) Inventors: Paul A. Colussi, Gloucester, MA 3, 2006, provisional application No. 60/875,917, filed (US); Thomas C. Evans, JR., on Dec. 20, 2006. Topsfield, MA (US); Christopher O O H. Taron, Essex, MA (US) Publication Classification (51) Int. Cl. Correspondence Address: 6. 245 3: ) HARRIET M. STRIMPEL, D. Phil. CI2N 9/16 6. 3. New E...

AzuFluor® 435-DPA-Zn, an azulene fluorophore bearing two zinc( ii )-dipicolylamine receptor motifs, exhibits fluorescence enhancement in the presence of adenosine diphosphate.

II. Triosephosphate Isomerase ....................................... .432 A. Isotopic Labeling to Reveal Mechanism ...................... .432 B. Isotope Effects to Reveal Reaction Energetics ................. .433 1. Transfer Experiments ................................. .434 2. Discrimination Experiments ............................ .435 3. Exchange vs. Conversion Experiments ..................