Aeromonas hydrophila secretes a number of degradative enzymes and toxins into the external milieu via the type II secretory pathway or secreton. ExeA is an essential component of this system and is necessary for the localization and/or multimerization of the secretin ExeD. ExeA contains two sequence motifs characteristic of the Walker superfamily of ATPases. Previous examination of substitution...

Cell-penetrating peptides and proteins (CPPs) are important tools for the delivery of impermeable molecules into living mammalian cells. To enable these cells to internalize proteins fused to common oligohistidine affinity tags, we synthesized an artificial cell surface receptor comprising an N-alkyl derivative of 3beta-cholesterylamine linked to the metal chelator nitrilotriacetic acid (NTA). ...

A man, who had been treated for infantile hypertrophic pyloric stenosis (PS), was found to have 3 sons with the same condition. A genealogical table of his family showed that both his parents had relatives with PS. So far as it was known, none of his wife's relatives had the condition. It is suggested that the man's parents carried genes predisposing to PS and transmitted these to him in such q...

This paper asks whether population growth is conducive to the sustainability of cooperation. A simple model is developed in which farmers who live around a circular lake engage in trade with their adjacent neighbors. The payoffs from this activity are governed by a prisoner's dilemma "rule of engagement." Every farmer has one son when the population is not growing, or two sons when it is growin...

Mirza Fath Ali Akhundzadeh is considered one of the most important and influential personalities in the religious-social life of contemporary Iran. He began his cultural activities writing dramas and criticizing the religious-social situation of the society he lived in. He said that this resembled Protestantism. In addition to this, he also dealt theoretically with the criticism of religion and...

54-year-old male patient was admitted in endocrine ward and referred to our hospital for psychiatric consult due to malaise symptoms , dysphoric mood, irritability, insomnia, loss of appetite, increasing the amount of speech, lack of enjoyment of life, hopelessness, thoughts of worthlessness ,thoughts of death (these symptoms was started from 4 months ago ,after some career change ). other symp...

PURPOSE The purpose of this study was to investigate the influence of childhood parental bonding on emotional distress experienced by primary caregiving sons for a parent with dementia. DESIGN AND METHODS Data from the 40 participants were obtained using the Parental Bonding Inventory (PBI), Brief Symptom Inventory (BSI), and Caregiver Survey Questionnaire (CSQ). A multivariate analysis of va...