ABST RACT The objective of this immunohistochemical study was to examine the expression of caspase-3,-5,-7, and -9 in sheep pox lesions in 15 naturally infected crossbred merino lambs. Sheep pox was diagnosed based on typical gross and histopathological lesions in the skin and visceral organs that were evaluated pathologically and immunohistochemically. Macroscopically, lesions were observed in...

There has been significant interest in developing depth-selective optical interrogation of biological tissue in general and of superficial (e.g., mucosal) tissue in particular. We report an in vivo polarization-gating fiber-optic probe that obtains backscattering spectroscopic measurements from a range of near-surface depths (100-200 microm). The design and testing was performed with polarized ...

Specimens from 7 patients with normal breast tissue 26 patients with benign breast lesions (6 fibroadenomas, and 4 intraductal papillomas, 2 mammae lactantes, 10 cases of cystic disease and 4 fibrotic lesions) were studied by immunocytochemistry and electron microscopy. Excretory epithelial cells in 2 of the 4 papillomas were immunostained for NSE. Myoepithelial cells were frequently stained as...

Photothermal therapy (PTT) at present, following the temperature definition for conventional thermal therapy, usually keeps the temperature of lesions at 42-45 °C or even higher. Such high temperature kills cancer cells but also increases the damage of normal tissues near lesions through heat conduction and thus brings about more side effects and inhibits therapeutic accuracy. Here we use tempe...

Five specimens of normal mammary tissue and 53 primary breast carcinoma lesions were tested for expression of HLA antigens and components of the antigen-processing machinery by immunohistochemical staining. The expression of transporter associated with antigen processing (TAP) 1, TAP2, and HLA class I antigens in breast carcinoma lesions was significantly associated with tumor grading. Like nor...

Background: Isoproterenol, a β-adrenergic agonist, may induce myocardial infarction when used in high dosage rats. This study was conducted to evaluate the effect of ethanol extract Kleinhovia hospita leaves on cardiac biomarkers and structures rats induced by isoproterenol. Methods: Male (n=30) were assigned as normal controls or treatment groups. The groups received pretreatments, either plac...

OBJECTIVE The study summarizes results of karyometric measurements in epithelial cells of the colorectal mucosa to document evidence of a field effect of preneoplastic development among patients with colorectal adenocarcinoma or adenoma. METHODS Karyometric analyses were done on high-resolution images of histologic sections from 48 patients with colorectal adenocarcinomas and 44 patients with...

The Kansai BNCT Medical Center has a cyclotron based epithermal neutron source for clinical Boron Neutron Capture Therapy. system accelerates proton to an energy of 30 MeV which strikes beryllium target producing fast neutrons are moderated down use. While studies in the past have shown be highly effective malignant melanoma skin, apply superficial lesions using this it is necessary shift therm...

Background. Reliable immunohistochemical assays to assess the definitive role of mast cells (MCs) and angiogenesis in the pathogenesis of oral reactive lesions are generally not available. The aim of the present study was to evaluate mast cell counts (MCC) and microvessel density (MVD) in oral reactive lesions and determine the correlation between MCC and MVD. Methods. Seventy-five cases of rea...

PURPOSE: Refractive index (RI) is unique in discriminating various tissues. It is dependent on water and solid components such as protein and phospholipid of brain tissue resembling hydrogel. Our purpose was to determine RI of normal and pathological tissues of brain from the MR T2 relaxation time (T2 value) to determine relative water and solid contents of a tissue and discriminate various pat...