نتایج جستجو برای: normal tissue complication probability
تعداد نتایج: 1618256 فیلتر نتایج به سال:
PURPOSE To establish a multivariate normal tissue complication probability (NTCP) model for radiation-induced hypothyroidism. METHODS AND MATERIALS The thyroid-stimulating hormone (TSH) level of 105 patients treated with (chemo-) radiation therapy for head-and-neck cancer was prospectively measured during a median follow-up of 2.5 years. Hypothyroidism was defined as elevated serum TSH with d...
Article type: Original Article Introduction: The ultimate goal of radiation treatment planning is to yield a high tumor control probability (TCP) with a low normal tissue complication probability (NTCP). Historically dose volume histogram (DVH) with only volumetric dose distribution was utilized as a popular tool for plan evaluation hence present study aimed to compare the radiobiological effec...
Severe acute dysphagia commonly results from head and neck radiotherapy (RT). A model enabling prediction of severity of acute dysphagia for individual patients could guide clinical decision-making. Statistical associations between RT dose distributions and dysphagia could inform RT planning protocols aiming to reduce the incidence of severe dysphagia. We aimed to establish such a model and ass...
In this research, modeling tree height distributions of beech in natural forests of Masal that is located in Guilan province; was investigated. Inventory was carried out using systematic random sampling with network dimensions of 150×200 m and area sample plot of 0.1 ha. DBH and heights of 630 beech trees in 30 sample plots were measured. Beta, Gamma, Normal, Log-normal and Weibull prob...
Background and PurposeRadiation-induced brainstem necrosis after proton therapy is a severe toxicity with potential association to uncertainties in the relative biological effectiveness (RBE). A constant RBE of 1.1 assumed clinically, but known vary linear energy transfer (LET). LET-inclusive predictive models may therefore be beneficial during treatment planning. Hence, we aimed construct desc...
PURPOSE Using current radiobiologic models and biologic parameters, we performed an exploratory study of the clinical consequences of hypofractionation in prostate cancer radiotherapy. METHODS AND MATERIALS Four hypofractionated treatment regimens were compared with standard fractionation of 2 Gy x 39 for prostate carcinoma using a representative set of anatomical structures. The linear-quadr...
Normal liver complications have not been observed in Y-90 microsphere therapy of hepatic tumors [selective internal radiation (SIR)], despite clinical studies reporting estimated absorbed doses to normal liver between 100 and 150 Gy. The purpose of the study was to see whether predictions of normal tissue complication probability (NTCP) models for liver based on clinical data from external beam...
BACKGROUND Linear Accelerator-based Intensity Modulated Radiation Therapy (IMRT), either as step-and shoot (SS) or in dynamic mode, is now considered routine in the definitive management of head and neck squamous cell carcinoma (HNSCC). Helical TomoTherapy (HT) is a new platform to deliver IMRT. This study aims to compare step-and-shoot Intensity Modulated Radiation Therapy (SS IMRT) with dynam...
Introduction: Relapsing polychondritis is a rare autoimmune disorder which is associated with inflammation of the auricular and costochondral cartilages and may involve ocular tissue and laryngotracheobronchial tree in some occasions. This inflammatory destructive disease can potentially disrupt the structure, function and integration of cartilages. The common age of involvement is 40 to 60 yea...
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