نتایج جستجو برای: normal data conversion cox
تعداد نتایج: 2984912 فیلتر نتایج به سال:
Introduction: Migraine is a common debilitating headache with reversible pain attacks associated with temporal changes in the diameter of head blood vessels. According to the International Classification for the Headache Society, migraineurs are divided into two main categories: migraine with aura and migraine without aura. The present study aimed to investigate the association between COX-2-7...
Cyclooxygenase (COX), also referred to as prostaglandin endoperoxide synthase, is the rate-limiting enzyme for the metabolic conversion of arachidonic acid to prostaglandins (PGs) and related eicosanoids. Some human breast cancers synthesize large quantities of PGE2, but the regulatory mechanisms involved are unclear. We have examined the expression of the two isoforms of this enzyme, COX-1 and...
Cyclooxygenases (COXs) are enzymes that take part in a complex biosynthetic cascade that results in the conversion of polyunsaturated fatty acids (PUFAs) to prostaglandins (PGs) and thromboxanes (TXs). Their main role is to catalyze the transformation of AA into the intermediate PGH2, which is the procursor of a variety of prostanoids (PTS) with diverse and potent biological actions. COXs have ...
PURPOSE Following the recent discovery of an abnormal expression of the p53 gene in the epithelium in pterygium, some researchers felt that pterygium is a tumor rather than a degenerative disease. Ultraviolet (UV) radiation has been reported to be associated with pterygium formation, however the mechanism whereby UV induces uncontrolled proliferation in pterygial cells is unclear. Because cyclo...
The aim of this study was to evaluate expression of COX-1 in renal cell carcinoma (RCC) and its prognostic value. mRNA of COX-1 was detected in 42 paired RCC and adjacent normal tissues with quantitative real- time polymerase chain reaction (qRT-PCR). Expression of COX-1 was also evaluated in 196 RCC sections and 91 adjacent normal tissues with immunohistochemistry. Statistical analysis was per...
By existing censor and skewness in survival data, some models such as weibull are used to analyzing survival data. In addition, parametric and semiparametric models can be obtained from baseline hazard function of Cox model to fit to survival data. However these models are popular because of their simple usage but do not consider unknown risk factors, that's why cannot introduce the be...
Cyclooxygenases (COXs) are key enzymes in the conversion of arachidonic acid into prostanoids which are involved in apoptosis and inflammation. Two distinct COXs have been identified: COX-1 which is constitutively expressed and COX-2 which is induced by different products such as tumor promoters or growth factors. Previously, we demonstrated that a plant steroid, diosgenin, was a new megakaryoc...
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