background and objectives: salvia species are important because of their medicinal, traditional and economical uses. they are used traditionally for treatment of several diseases. the genus salvia is represented in the iranian flora by 61 species of which, 17 are endemic.  in the present study, the phytochemical and biological effects of two iranian salvia species have been evaluated. methods: ...

the hawthorn fruits have been used as food and medicine for centuries. in the present study, pulp and seed extract of crataegus elbursensis rech. f. fruits belonging to the family rosaceae and native of northern part of iran were evaluated for the polyphenol contents, antiradical, antioxidant, and antibacterial activities. the total phenolic, flavonoid, and anthocyanin contents of methanolic pu...

PURPOSE There is increasing evidence to show cytoprotective effects of various flavonoid-rich extracts and the tissue-protective capacity of flavonoid-rich extract of sour cherry is due to flavonoid components of seeds. Sour cherry seed flavonoids were evaluated for their contribution to postischemic recovery related to endogenous carbon monoxide (CO) production in rat retinas subjected to isch...

background and aims: medicinal plants are a valuable resource for flavonoids extraction. prosopis fracta is one of the plants with medicinal properties. prosopis fracta was found in abundance in southern regions in iran. coersetin is medicinal substance found in the fruit of this plant. quercetin is used in treatment of cancer and viral infections. this study was conducted to determine the quer...

High performance liquid chromatography (HPLC) with diode array detection (DAD) and electrospray ionization tandem mass spectrometry (ESI/MS/MS) was used to analyze the main components in the methanol extract of Fructus Aurantii (FA) and the metabolites in rat biological samples after oral administration of the methanol extract of FA. There were 31 constituents identified in the extract of FA in...

This study documents the flavonoid constituents of seven Salvia species in Iran namely S.atropatana Bunge, S. limbata C. A. Mey, S. sclarea L., S. ceratophylla L., S. multicaulis Vahl.,S. hydrangea Dc. ex Benth., and S. eremophila Boiss. The studied species were collected fromtheir natural habitats in Iran and were analyzed for their flavonoid constituents using twodimensionalthin layer chromat...

cisplatin (cp) as an important anti-tumor drug causes nephrotoxicity mainly by oxidative stress and renin-angiotensin system (ras). since flavonoids have high antioxidant activity and probable role in the inhibition of ras, this study was designed to investigate the protective effect of hydroalcoholic extract and flavonoid fraction of morus alba leaves on cisplatin-induced nephrotoxicity in rat...

A novel flavonoid glucoside, ruthenicunoid A (1), together with eight known substances, were isolated from the fruits of Lycium ruthenicun Murr. Their structures were elucidated by extensive spectroscopic data and chemical methods. Especially, the absolute configuration of glucose residue in 1 was assigned by acid hydrolysis followed by derivatization and GC analysis. Biological evaluation towa...

High performance liquid chromatography (HPLC) with diode array detection (DAD) and electrospray ionization tandem mass spectrometry (ESI/MS/MS) was used to analyze the main components in the methanol extract of Fructus Aurantii (FA) and the metabolites in rat biological samples after oral administration of the methanol extract of FA. There were 31 constituents identified in the extract of FA in...