نتایج جستجو برای: non small cell lung cancer nsclc
تعداد نتایج: 4070744 فیلتر نتایج به سال:
Holgersson, G. 2017. Prognostic Factors in Non-Small Cell Lung Cancer (NSCLC). Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1359. 84 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-513-0043-6. Background: Non-small cell lung cancer (NSCLC) is the cancer disease with the highest mortality globally. About 75% of NSCLC patients are diagnosed in an ...
Lung cancer is the leading cause of cancer death worldwide. Non-small cell lung cancer (NSCLC) accounts for 85% of total lung cancers; 40% to 60% of NSCLC patients die of cancer recurrence after cancer resection. Since GLK (also named MAP4K3) induces activation of NF-κB, which contributes to tumor progression, we investigated the role of GLK in NSCLC. GLK protein levels of 190 samples from pulm...
Interleukin-6 (IL-6) has been identified as an important growth regulator of lung cancer cells. Elevation of serum levels of IL-6 has been found in a subpopulation of lung cancer patients, but rarely in patients with benign lung diseases. Approximately 15% of non-small cell lung cancer (NSCLC) tumors exhibit neuroendocrine (NE) properties (NSCLC-NE) and have been suggested to have the biologica...
Lung cancer is the most common globally, accounting for a quarter of all cancer-related deaths. Non-small cell lung (NSCLC) major subtype. Research in last few decades has led to identification key molecular targets resulting targeted therapies, such as use tyrosine kinase inhibitors (TKIs) targeting epidermal growth factor receptors (EGFR). EGFR-TKIs themselves have evolved through generations...
Background and purpose: Lung cancer is a public health problem worldwide. Identifying the epidemiological characteristics of involved patients can play an important role in designing analytical studies. The aim of this study was to identify the epidemiology of patients with lung cancer attending Tooba clinic and Imam Khomeini Hospital in Sari, Iran. Materials and methods: In this descriptive s...
Mutations in the mtDNA genome have long been suspected to play an important role in cancer. Although most cancer cells harbor mtDNA mutations, the question of whether such mutations are associated with clinical prognosis of lung cancer remains unclear. We resequenced the entire mitochondrial genomes of tumor tissue from a population of 250 Korean patients with non-small cell lung cancer (NSCLC)...
Staging of non-small lung cancer (NSCLC) uses the TNM classification and is undertaken to identify those patients who are surgical candidates, either initially or after chemo-radiotherapy, and to differentiate patients who will be treated radically from those requiring palliation and to plan radiotherapy fields. Computed tomography and magnetic resonance imaging (MRI) are used in staging and pr...
Aggressive neuroendocrine lung cancers, including small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC), represent an understudied tumor subset that accounts for approximately 40,000 new lung cancer cases per year in the United States. No targeted therapy exists for these tumors. We determined that achaete-scute homolog 1 (ASCL1), a transcription factor required for proper develo...
Lung cancer represents the most common form of cancer, accounting for 1.8 million deaths globally in 2020. Over last decade treatment advanced and metastatic non-small cell lung have dramatically improved largely thanks to emergence two therapeutic breakthroughs: discovery immune checkpoint inhibitors targeting oncogenic driver alterations. While these therapies hold great promise, they face sa...
Non-small cell lung cancer (NSCLC) poses a serious threat to people’s health. Its morbidity and mortality are among the highest all malignant tumors, there is an urgent need for more effective new treatment methods. In recent years, NSCLC immunotherapy has made great progress, first PD-1 inhibitor nivolumab (Nivolumab, O drug) was approved by US Food Drug Administration (FDA) in March 2015, app...
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