نتایج جستجو برای: non small cell lung
تعداد نتایج: 3512205 فیلتر نتایج به سال:
BACKGROUND As part of an evaluation of the lung cancer surgery at Akershus University hospital we wanted to describe the lung cancer surgery programme, assess 30-day mortality and review complications. MATERIAL AND METHOD We retrospectively examined medical records of all patients undergoing potentially curative surgery for non-small-cell lung cancer. RESULTS The 99 patients operated on wer...
Epidemiological studies have demonstrated a strong association between tobacco use and lung cancer; however, the genetic targets of these carcinogens and the role of other environmental agents in this process have yet to be defined. We examined the contribution of alcohol use and cigarette smoking to p53 gene mutations in patients with non-small cell lung cancer. Mutations of the p53 gene were ...
Chemotherapy: is it still enough? The major progresses in understanding cancer biology and the mechanism of oncogenesis have allowed the development of several potential molecular target drugs for cancer treatment, which are components of signaling pathways or metabolic processes contributing to the acquisition of cancer phenotype. A general better tolerability, owing to a milder toxicity profi...
The treatment of advanced non-small-cell lung cancer (NSCLC is based on the combination of platin and one of the following agents: taxanes, gemcitabine, vinorelbine or irinotecan. There are no significant differences in efficacy among these combinations suggesting that the maximum efficacy has been reached. In this review, we will consider the mechanisms of chemoresistance of the five groups of...
The sequestration of rat leukocytes and bone marrow cells by the lung vasculature was studied using an isolated perfused rat lung preparation. The passage of latex particles of 7.6 µm in diameter and non-hematopoietic cells through the lung blood vessels was also studied. Leukocytes and bone marrow cells were reversibly sequestered from circulation, whereas, latex particles and non-hematop...
This corrects the article DOI: 10.1038/srep09918.
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