OBJECTIVE To explore the role of combined detection of carcinoembryonic antigen (CEA) and neutrophil-to-lymphocyte ratio (NLR) in the prognostic assessment of colorectal cancer (CRC). METHODS We investigated preoperative NLR and CEA in 125 surgical CRC patients, determined the patients' thresholds by receiver operating characteristic (ROC) curve analysis, and assessed their prognostic values ...

Noninvasive evaluation of brachial artery diameter (pulsed Doppler velocimetry) and pulse wave velocity (strain gauge mechanography) was performed in 23 normal subjects and 49 patients with uncomplicated essential hypertension. Pulsatile arterial function was described in terms of derived characteristic impedance and arterial compliance. Compared with normal controls, hypertensive patients had ...

Background Sialyltransferase ST6GalNAc-1 is highly expressed in tumor cells and associated with tumor aggressiveness and poor prognosis. In the present study, we aimed to investigate the clinical and prognostic significance of sialyltransferase ST6GalNAc-1 in patients with non-metastatic ccRCC. Results High expression of ST6GalNAc-1 in tumor tissue was an independent prognostic factor for ove...

The prognosis of intrahepatic cholangiocarcinoma (ICC) remains poor whereas predictive models for survival prediction in ICC patients following curative resection are limited. Herein, we established a novel inflammation-based score derived from preoperative albumin to gamma-glutamyltransferase ratio (AGR) and evaluated its prognostic significance in ICC patients underwent curative resection. Pr...

Chapter 2. Methods of calculation of Nonlinear interactions in sound beams Small parameters used in the calculation of wave interactions Solution of the equations of hydrodynamics by the method of successive approximations Calculation of the secondary field by the Green's function method: The Westervelt formula Estimates of the basic characteristics of parametric radiators by means of nomograms...

To the Editor.-According to the threshold model, the choice of a particular clinical strategy, observation vs testing vs treatment, is dictated by the probability of disease’s exceeding two relevant threshold probabilities.* If the probability of disease is below the testing threshold (p,l, testing should be withheld. If the probability of disease is above the treatment threshold (p,), then tre...

Decades from now, when we fully understand the biologic basis for the clinical heterogeneity of prostate cancer, we will think of the current era as the Golden Age of Prostate Nomograms. Driven by the paucity of randomized data to guide treatment decisions, particularly in localized disease, nomograms have proliferated. Currently, there are more than 40 published prostate cancer nomograms to he...

BACKGROUND IRF5 is one member of IRFs family, and is critical for host immunity and cell response. In the present study, we sought to search the clinical and prognostic value of IFR5 in patients with non-metastatic ccRCC. RESULTS IRF5 proved to be an adverse independent prognostic factor for overall survival (p < 0.001) and recurrence free survival (p = 0.002). The newly built nomograms could...

OBJECTIVE To systematically review the literature and provide an update and integration of existing peer-reviewed guidelines with recent systematic reviews and with primary studies related to the early recognition and management of prostate cancer in primary care. DATA SOURCES We searched MEDLINE and EMBASE for relevant articles. The quality of the evidence to support existing guideline recom...

We enrolled a total of 277 patients who received nephrectomy due to clear cell renal cell carcinoma (ccRCC) in Zhongshan Hospital from Jan 2005 to Jun 2007. Immunohistochemistry was performed to evaluate the impact of CLEC-2 positive cell infiltration on the overall survival (OS) and recurrence-free survival (RFS) of patients with ccRCC. Kaplan-Meier analysis showed that high CLEC-2 positive ce...