Pain is more than merely nociception and response, but rather it encompasses emotional, behavioral and cognitive components that make up the pain experience. With the recent advances in imaging techniques, we now understand that nociceptive inputs can result in the activation of complex interactions among central sites, including cortical regions that are active in cognitive, emotional and rewa...

To describe the role of internet and cognitive biases in controversy surrounding chronic Lyme disease. The attribution but aspecific symptoms to borreliosis is a source worldwide controversy. Some patients attribute their even though, fact, they have functional somatic syndrome. These patients’ diagnostic therapeutic wandering contributes above suffering. Internet has deregulated information ma...

Background Placebo-controlled oral drug provocation tests (DPTs) are an important step in drug hypersensitivity diagnosis. Administration of placebo (an inert sostance not detectable from drug) is recommended to avoid psychological influences on the interpretation of DPT results, however actually little is known about how to deal a reaction to placebo and how to go further with the diagnostic p...

Computational modeling of emotion, physiology and personality is a major challenge in order to design believable virtual humans. These factors have an impact on both the individual behavior and the collective one. This requires to take into account the empathy phenomenon. Furthermore, in a crisis simulation context where the virtual humans can be contaminated by radiological or chemical substan...

Any medical or psychosocial treatment has two components, one associated with the specific effects of the treatment itself, and the other related to the treatment context, individual perception, imagination, subjective meaning and psychobiological response. Psychopharmacotherapy is a context dependent practice because different contexts affect the meaning of biological variables in different wa...