Household gas appliances produce nitrogen dioxide (NO2), which may be associated with an increase in symptoms in asthmatics. The relationship between indoor NO2 exposure, and respiratory symptoms in people with asthma was evaluated. Self-reported asthmatics (n=125) wore lapel badges that measured NO2 daily over 6 weeks at home. Outdoor pollutants, spores and meteorological parameters were measu...

The AMAXDOAS instrument is an airborne multi-axis DOAS instrument covering the spectral range from 300 to 600 nm. During one flight of the SCIAVALUE campaign on 19 March 2003, the AMAXDOAS onboard the DLR Falcon detected tropospheric NO2 over Europe under both cloudy and cloud free conditions. By combining the measurements in nadir and zenith direction, and analysing the spectra in the UV and t...

MIPAS/ENVISAT data of nighttime NO2 volume mixing ratios (VMR) from 2007 until 2012 between 40 km and 62 km altitude are compared with the geomagnetic Ap index and solar Lyman-α radiation. The local impact of variations in geomagnetic activity and solar radiation on the VMR of NO2 in the lower mesosphere and upper stratosphere in the Northern Hemisphere is investigated by means of superposed ep...

BACKGROUND Radical regulations to improve air quality, including traffic control, were implemented prior to and during the 2008 Beijing Olympic Games. Consequently, ambient concentrations of nitrogen dioxide (NO2) and particular matter 10 micrometers or less (PM10), were reduced in a distinct and short window of time, which presented a natural experiment for testing the relationships between ma...

The production of nitrate (NO3-) and nitrite (NO2-) from macrophage-derived NO was studied using EPR and spin trapping. The formation of NO3- was determined via EPR in reactions involving the iron-binding protein, lactoferrin. The formation of NO2- was determined via EPR/spin trapping in the reaction between NO2- and H2O2. Dissolved nitric oxide (NO.) was reacted with lactoferrin yielding an EP...

Nitrogen dioxide (NO2) is a free radical-producing oxidant gas. Inhalation of NO2 could cause airway inflammation, and decrease immune function. This experiment tested the hypothesis that exposure to NO2 would: 1) increase leukocytes in bronchoalveolar lavage (BAL); and 2) change the distribution of lymphocyte subsets and activation in BAL and peripheral blood (PB). Using a counter-balanced, re...

The traditional on-road emissions remote sensing technique has been enhanced with the ability to monitor not only CO, CO2, HC and NO, but also SO2, NH3 and NO2. Modern diesel powered vehicles, particularly in Japan and Europe are equipped with diesel particle filters (DPFs). These traps are frequently designed to be self regenerating by means of a prior catalytic oxidation of the exhaust NO to ...

Abstract. Nitrogen dioxide (NO2), is a pollutant that is toxic by inhalation and there is evidence that long-term exposure to this, at high concentrations, has adverse health effects, namely in respiratory and cardiovascular systems. The goal of this study is to characterize the spatial and temporal evolution of NO2 concentration levels, taking into account that environmental data often incorpo...

Nitrated fatty acids are endogenously present in human and animal tissues, as well as in plant-derived oils. In particular, 10-nitro oleic acid (10-NO2-OA) potently induces Nrf2-dependent antioxidant gene expression and inhibits TLR4/NF-κB signaling, thus promoting an overall cyto-protective and anti-inflammatory response. 10-NO2-OA has been extensively tested in animal models and is currently ...

BACKGROUND Repeated daily exposure of healthy human subjects to NO2 induces an acute airway inflammatory response characterised by neutrophil influx in the bronchial mucosa AIMS To assess the expression of NF-kappaB, cytokines, and ICAM-1 in the bronchial epithelium. METHODS Twelve healthy, young non-smoking volunteers were exposed to 2 ppm of NO2/filtered air (four hours/day) for four succ...