and concentrations of the nitrogen mustard, it was possible to inhibit the synthesis of DNA more than that of RNA and to inhibit synthesis in a sensitive tumor without inhibiting synthesis in a bilaterally growing resistant tumor. Other studies (23) showed that multidose treatment of hamsters bearing plasmacytomas with cyclophosphamide [2-[bis(2chloroethyl)amino]-2H-1,3,2-oxazaphosphorinane 2-o...

β-glucosidase (E.C. 3.2.1.21), an enzyme involved in cellulose degradation, plays an important role in the soil organic carbon cycle. Cellulose is the most abundant organic compound in the biosphere so a product of its enzymatic hydrolysis is important as an energy source for soil microorganisms. Since β-glucosidase is very sensitive to different factors, determination of its activity might be ...

Information on soil nutrition level or pollution can lead to the establishment of some recommendations a strategic decision-making program for reference area development. The specific analysis is essential both from an economic point view and environmental view. To achieve adequate management nutrients into agricultural field, it necessary conduct agrochemical study at interval 3–5 years, in wh...

The aim of the study was to examine sperm viability of Pinzgau bull insemination doses following longor short-term storage. Insemination doses, provided by Slovak Biological Services Inc. (Lužianky, Slovak Republic), were slow-frozen and stored in containers with liquid nitrogen for 1 18 years. The sperm samples were divided, according to the length of storage, to the short-term ( ≤ 15 years) a...

Dilantin has long been known to result in hyperplasia of the gingiva (1) and to increase the tensile strength of rat skin (2). We have shown that daily intraperitoneal injections of 25 mg of Dilantin resulted in marked increases in the insoluble collagen, hexosamine, and insoluble noncollagenous protein (scleroprotein) content of rat skin (3). Four daily doses of the drug were sufficient to sig...

In the past 2 years, an increasing number of reports have appeared in the medical literature that suggest that the use of bisphosphonates, especially intravenous bisphosphonates, is associated with osteonecrosis of the jaw (ONJ). The majority of these reports are in patients with multiple myeloma, breast cancer, or other malignancies. In connection with these malignancies, the patients were rec...

Many studies on biological effects of neutrons involve dose responses of neutrons, which rely on accurately determined absorbed doses in the irradiated cells or living organisms. Absorbed doses are difficult to measure, and are commonly surrogated with doses measured using separate detectors. The present work describes the determination of doses absorbed in the cell layer underneath a medium co...

We have previously shown that the intrapleural injection of mitozantrone but not bleomycin resulted in pleural fibrosis. Mechlorethamine hydrochloride (nitrogen mustard) was used extensively in the past to control malignant effusions, with relatively good success. The objective of this study was to determine if the intrapleural injection of nitrogen mustard would produce pleural sclerosis in ou...

Montane soils disturbed by forest loss, fire and livestock, are highly susceptible to erosion, leading rapid degradation that reduces their fertility. Soil hampers native restoration efforts, resulting in low natural recruitment rates slow growth field plantations. In order contribute more effective strategies, we conducted a study test the hypothesis early addition of fertilizers degraded mont...

An experimental trial was carried out in the two successive seasons of 2010 and 2011 to investigate the effect of Chitosan, organic (cattle manure and compost) and inorganic fertilizers (NPK) on vegetative growth and productivity of cowpea plants. Chitosan solution was sprayed three times after 30, 45 and 60 days from seed sowing at concentrations of 1, 3 and 5 % until runoff. Data showed that ...