Background: Nitazoxanide (NTZ) is a broad spectrum antimicrobial agent with poor aqueous solubility and low bioavailability. Thus, the generation of new solid forms NTZ relevant to improve its unfavorable properties. The present study deals application mechanochemistry for preparation alternate NTZ, using saccharine (SAC) as coformer. Methods: NTZ-SAC mixtures were prepared by neat liquid-assis...

Introduction: Cryptosporidiosis is an enteric parasitic infection that is associated with a self limiting illness in healthy patients. However, it can cause prolonged and severe life threatening complications especially in immunocompromised patients. The most common symptoms associated with Cryptosporidial infection include abdominal pain and diarrhea. In the absence of appropriate stool studie...

G A A b st ra ct s disease with hepatocellular carcinoma (HCC). Microsporidial infection was positive on wet preparation in 8(2.7%), in 11(3.7%) on Trichrome staining and in 13(4.3%) on PCR. Microsporidia was diagnosed with PCR in 8(61%) (p= 0.002) with IBS-D, 4(31%) with HCC and 1(8%) with functional dyspepsia. Conclusion: Microsporidial infection may be associated with IBS-D. PCR for microspo...