NOD2 contributes to the innate immune response and to the homeostasis of the intestinal mucosa. In response to its bacterial ligand, NOD2 interacts with RICK and activates the NF-κB and MAPK pathways, inducing gene transcription and synthesis of proteins required to initiate a balanced immune response. Mutations in NOD2 have been associated with an increased risk of Crohn's Disease (CD), a disa...

BACKGROUND We aimed to compare the analgesia quality of caudal block of low volume, high concentration bupivacaine to the conventionally used volumes and concentrations of the drug in neonates undergoing circumcision with sole caudal anesthesia. METHODS Fifty neonates, undergoing circumcision were randomly assigned to low volume high concentration (group LVHC, n=25) and control groups (group ...

OBJECTIVE To evaluate the impact of manual vibrocompression and nasotracheal suctioning on heart (hr) and respiratory (rr) rates, peripheral oxygen saturation (SpO(2)), pain and respiratory distress in infants in the postoperative period of a cardiac surgery. METHODS Randomized controlled trial, in which the assessments were performed by the same physiotherapist in two moments: before and aft...

Tissue engineering benefits from novel materials with precisely tunable physical, chemical and mechanical properties over a broad range. Here we report a practical approach to prepare Bombyx mori silk fibroin hydrogels using the principle of non-solvent induced phase separation (NIPS). A combination of reconstituted silk fibroin (RSF) and methanol (non-solvent), with a final concentration of 2....

Background: Neonates are more sensitive to pain and likely to suffer from its long-term complications. Therefore, various methods including non-nutritive sucking, sensory stimulations, and various supportive interventions are employed to relieve pain in newborns. Aim: This study aimed to compare the effects of Yakson therapeutic touch and heel warming on pain caused by heel stick procedure, vit...

With the advancements in various data-mining and social network related approaches, data-sets with a very high feature dimensionality are often used. Various information theoretic approaches have been tried to select the most relevant set of features and hence bring down the size of the data. Most of the times these approaches try to find a way to rank the features, so as to select or remove a ...

Standard recurrent nets cannot deal with long minimal time lags between relevant signals. Several recent NIPS papers propose alternative methods. We rst show: problems used to promote various previous algorithms can be solved more quickly by random weight guessing than by the proposed algorithms. We then use LSTM, our own recent algorithm, to solve a hard problem that can neither be quickly sol...

Computational models of the hippocampal-region provide an important method for understanding the functional role of this brain system in learning and memory. The presentations in this workshop focused on how modeling can lead to a unified understanding of the interplay among hippocampal physiology, anatomy, and behavior. Several approaches were presented. One approach can be characterized as "t...

For an n-variate order-d tensor A, define Amax := sup‖x‖2=1〈A, x ⊗d〉 to be the maximum value taken by the tensor on the unit sphere. It is known that for a random tensor with i.i.d. ±1 entries, Amax . √ n · d · log d w.h.p. We study the problem of efficiently certifying upper bounds on Amax via the natural relaxation from the Sum of Squares (SoS) hierarchy. Our results include: When A is a rand...