Three patients with late stage primary biliary cirrhosis were found to have appreciable night blindness. Serum vitamin A concentrations were low in all three patients despite regular intramuscular supplementation in two. All patients responded dramatically to high dose oral supplementation, with full recovery of adaptation to dark and visual fields. Oral rather than intramuscular vitamin A supp...

introduction sectoral retinitis pigmentosa (rp) is a rare clinical condition. case presentation we present a 60-year-old female with a history of mild night blindness and decreased vision in the left eye for about 15 years. conclusions fundus examination revealed retinal pigmentary changes in the inferotemporal sector and reduced arterial caliber. in addition, fundus autofluorescence, fluoresce...

Retinitis pigmentosa (RP) is an inherited retinal dystrophy caused by the loss of photoreceptors and characterized by retinal pigment deposits visible on fundus examination. Prevalence of non syndromic RP is approximately 1/4,000. The most common form of RP is a rod-cone dystrophy, in which the first symptom is night blindness, followed by the progressive loss in the peripheral visual field in ...

purpose : to determine the anatomical site and underlying causes of blindness and severe visual impairment (bl/svi), in schools for the blind in east azerbaijan state with determining potentially preventable and treatable causes. methods : between october 2003 and november 2004 a total of 124 students attending three schools for the blind in east azerbaijan state were examined clinically and da...

Two distantly related, two- to three-year-old male Akita dogs developed partial or complete night blindness which progressed to day blindness. Clinical features were attenuated retinal blood vessels, diffuse exaggerated tapetal reflex, and hyperreflective horizontal lines in the tapetal fundus. The principal histologic change was regional photoreceptor cell degeneration. Areas of moderately atr...

Vitamin A deficiency in India ranks among the four major public health nutritional problems affecting not only children but also women of the reproductive age group and others. However, a noticeable change that has occurred in the last two decades is the very marked decline in serious forms of this deficiency leading to a decline in keratomalacia and hence nutritional blindness. The problem to ...

purpose: to describe the variability of ocular and systemic findings in two brothers with gaucher's disease. case report: ophthalmic, general clinical evaluation and enzymatic studies were performed in two brothers, 14 and 7 years old with gaucher’s disease. mental retardation, occipital meningomyelocele and gaucher cells in bone marrow in addition to high myopia and various fundus abnorma...