Here we describe the case of an unfortunate 26 year old woman who developed a fatal combination of autoimmune hemolytic anemia (AIHA), hemophagocytic lymphohistiocytosis (HLH), and thrombotic thrombocytopenic purpura (TTP). Her initial clinical picture looked that of typical autoimmune hemolytic anemia but when she was refractory to standard therapy and her course progressed, alternative diagno...

Chronic cold agglutinin disease (CAD) is an acquired autoimmune hemolytic anemia (AIHA); usually due to the production of a monoclonal immunoglobulin M (IgM) protein directed against polysaccharide antigens on red blood cells.1,2 An occult lymphoproliferative disorder is often responsible for the production of the IgM paraprotein in patients with symptomatic CAD.3 The discovery of an underlying...

The Fas (CD95) gene is among critical genetic factors in some autoimmune diseases, which are characterized by autoantibody (autoAb) productions. In mice, mutations in the Fas gene cause lymphoproliferation (lpr) which predominantly develops glomerulonephritis, whereas the mutations in human cause autoimmune lymphoproliferative syndrome (ALPS) characterized by autoimmune hemolytic anemia (AIHA) ...

Amaranthus palmeri S. Wats., or commonly Palmer amaranth, is an invasive plant species that has invaded many countries worldwide and causes significant yield losses to annual spring crops. amaranth biotypes were detected in maize sorghum fields Western Greece cotton Central 2020. The infestations recorded both inside the crops margins of fields, indicating could be characterized as weed for the...

background: ataxia telangiectasia (at) is one of the combined immunodeficiency syndromes with immunologic, neurologic, endocrinologic, hepatic and cutaneous abnormalities. regarding the fact that autoimmune disorders; such as autoimmune hemolytic anemia (aiha), are not generally expected in the course of at, we present a patient with an unusual presentation of these two conditions. case present...

Background Autoimmune hemolytic anemia is a hematologic disorder that is rarely observed in infants and young children. Most of the cases are associated with viral or bacterial infections. In some cases, AIHA can be characterized by a chronic course and an unsatisfactory control of hemolysis, thus requiring prolonged immunosuppressive therapy. Case report Especially in children younger...

Background: Ataxia telangiectasia (AT) is one of the combined immunodeficiency syndromes with immunologic, neurologic, endocrinologic, hepatic and cutaneous abnormalities. Regarding the fact that autoimmune disorders; such as autoimmune hemolytic anemia (AIHA), are not generally expected in the course of AT, we present a patient with an unusual presentation of these two conditions. Case present...

The combination of Antiphospholipid Antibody Syndrome (APS) and Autoimmune Haemolytic Anemia (AIHA) is extremely unusual. However, APS with underlying SLE has a well-documented link to Coomb’s positive AIHA. antibody syndrome autoimmune haemolytic anaemia can cause cerebral venous sinus thrombosis, which rare neurologic symptom. We reported 16- year-old girl the neurology ward dull aching heada...