Methods We searched in Pubmed and Cochrane-central-registerfor-controlled-trials for all NI RCTs of direct thrombin inhibitors (DTI) and direct inhibitors of factor Xa (DXAI) for prophylaxis of VTE. All NI trials had enoxaparin as their active comparator. Using the draft FDA guidelines for NI trials, we determined an NI margin, referred to as the reference NI margin, based on all published plac...

The crystal structure of the title compound, [Ni(C(6)H(6)N(4)S(2))(H(2)O)(4)][Ni(C(7)H(3)NO(4))(2)]·3H(2)O, consists of Ni(II) complex cations, Ni(II) complex anions and lattice water mol-ecules. The Ni(II) ions in both the complex cation and anion assume a distorted octa-hedral coordination geometry. O-H⋯O, N-H⋯O and C-H⋯S hydrogen bonds occur in the crystal structure.

The imido complex (dtbpe)Ni(N(2,6-(CHMe2)2C6H3)) reacts with CO and CNCH2Ph with addition at the Ni-N bond to give (dtbpe)Ni(C,N:eta 2-C(O)N(2,6-(CHMe2)2C6H3)) and (dtbpe)Ni(C,N:eta 2-C(NCH2Ph)N(2,6-(CHMe2)2C6H3)); both complexes react further with CO to liberate the isocyanate and carbodiimide ligands with formation of (dtbpe)Ni(CO)2.

Nickel–molybdenum (Ni–Mo) materials are widely used functional oxide catalysts for the hydrogen evolution reaction. In this work, we investigate the high activity of Ni–Mo by depositing size-controlled Ni nanocrystals (NCs) onto Mo substrates. We observe a synergistic increase in catalytic activity that does not scale with the Ni–Mo interface length. This evidence points to a bulk electronic in...

We find that the photoelectron angular distributions from the Fermi surface of a monolayer Ni film on Cu are identical to those from thick Ni films and single-crystal Ni(001), and agree well with theoretical predictions for bulk Ni. This bulklike behavior in the monolayer film is attributed to the short screening length of electrons in metals, the similarity of the Ni and Cu cores, and a hybrid...

The β-diketiminato nickel(I) complex K2[L(tBu)Ni(I)(N2(2-))Ni(I)L(tBu)] reacts with CO2 via reductive disproportionation to form CO and CO3(2-) containing products, whereas after employment of the Ni(I) precursor [L(tBu)Ni(I)(N2)Ni(I)L(tBu)] reductive coupling of CO2 was observed giving an oxalate bridged dinickel(II) complex. The addition of KC8 to the carbonate and oxalate compounds formed le...

Attenuated derivative rabies virus Ni-CE replicates in muscle cells less efficiently than does the parental pathogenic strain Nishigahara. To examine the mechanism underlying the less efficient replication of Ni-CE, we compared the activities of Ni-CE and Nishigahara phosphoproteins, viral interferon (IFN) antagonists, to suppress IFN-β promoter activity in muscle cells and we demonstrated a de...

In the title compound, [Ni(C(18)H(18)N(2)O(4))]·C(3)H(7)NO, the central Ni(II) atom is in a square-planar O(2)N(2) coordination environment. The planar Ni-salen moieties (r.m.s. deviation for the plane through the conjugated part of the Ni-salen group = 0.07 Å) form parallel stacks in the a-axis direction, with alternating Ni⋯Ni separations of 3.5339 (7) and 3.6165 (7) Å. In the crystal, there ...

Departing from the geodesic flow on a surface of negative curvature as a classic example of the hyperbolic chaotic dynamics, we propose an electronic circuit operating as a generator of rough chaos. Circuit simulation in NI Multisim software package and numerical integration of the model equations are provided. Results of computations (phase trajectories, time dependences of variables, Lyapunov...