Abstract Exploiting data on tens of millions housing transactions, we show that (1) house prices grew by less in manufacturing-heavy US regions, (2) this pattern is especially present for the lowest-value homes and (3) price declines coincided with worse labour market outcomes, consistent an income channel. Counterfactual accounting exercises reveal regional differences growth these are importa...

DNA double strand breaks (DSBs) are the most dangerous form of DNA damage and need to be repaired efficiently in order to maintain genomic stability. The kinase ATM becomes activated upon recognition of DSBs and transduces this into cell cycle checkpoint activation and DNA repair. There are two main pathways by which DSBs can be repaired: Non-homologous end joining (NHEJ) and homologous recombi...