نتایج جستجو برای: neutrophil gelatinase

تعداد نتایج: 43446  

Journal: :Brain : a journal of neurology 2005
Jian Wang Stella E Tsirka

Intracerebral haemorrhage (ICH) is an acute neurological disorder without effective treatment. Mechanisms of acute brain injury after ICH remain to be clarified. Although a few studies suggested a detrimental role for the gelatinase matrix metalloproteinase (MMP)-9 in ICH, the relationship between MMP-9 activity and acute brain injury after ICH is not determined. In this study, we first examine...

2014
Zheng Qiu Jianghai Chen Hanmei Xu Philippe E Van den Steen Ghislain Opdenakker Min Wang Jialiang Hu

Endotoxin shock is a life-threatening disorder, associated with the rapid release of neutrophil enzymes, including neutrophil collagenase/matrix metalloproteinase-8 (MMP-8) and gelatinase B/matrix metalloproteinase-9 (MMP-9). After activation, these enzymes cleave extracellular matrix components and cytokines and thus may contribute to shock syndrome development. MMP inhibitors have been sugges...

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