نتایج جستجو برای: neutral comet assay

تعداد نتایج: 307083  

Journal: :Science 2015
T Spohn J Knollenberg A J Ball M Banaszkiewicz J Benkhoff M Grott J Grygorczuk C Hüttig A Hagermann G Kargl E Kaufmann N Kömle E Kührt K J Kossacki W Marczewski I Pelivan R Schrödter K Seiferlin

Thermal and mechanical material properties determine comet evolution and even solar system formation because comets are considered remnant volatile-rich planetesimals. Using data from the Multipurpose Sensors for Surface and Sub-Surface Science (MUPUS) instrument package gathered at the Philae landing site Abydos on comet 67P/Churyumov-Gerasimenko, we found the diurnal temperature to vary betwe...

2015
Emily Winterburn

Long before women were allowed to become Fellows of the Royal Society, or obtain university degrees, one woman managed to get her voice heard, her discovery verified and her achievement celebrated. That woman was Caroline Herschel, who, as this paper will discuss, managed to find ways to fit comet discoveries into her domestic life, and present them in ways that were socially acceptable. Caroli...

2005
PETER C. THOMAS JOSEPH VEVERKA MICHAEL F. A’HEARN LUCY MCFADDEN MICHAEL J. S. BELTON JESSICA M. SUNSHINE

The Deep Impact mission will provide the highest resolution images yet of a comet nucleus. Our knowledge of the makeup and structure of cometary nuclei, and the processes shaping their surfaces, is extremely limited, thus use of the Deep Impact data to show the geological context of the cratering experiment is crucial. This article briefly discusses some of the geological issues of

Journal: :Current Biology 2001
Lisa A. Cameron Tatyana M. Svitkina Danijela Vignjevic Julie A. Theriot Gary G. Borisy

Polymerization of actin filaments is necessary for both protrusion of the leading edge of crawling cells and propulsion of certain intracellular pathogens, and it is sufficient for generating force for bacterial motility in vitro. Motile intracellular pathogens are associated with actin-rich comet tails containing many of the same molecular components present in lamellipodia, and this suggests ...

2007
Alina Błaszczyk Janusz Skolimowski

Ethoxyquin phosphate (EQ-P) and ethoxyquin hydrochloride (EQ-HCl) were synthesized and studied for genotoxic and antioxidant activities with the use of comet assay and micronucleus test performed on human lymphocytes. The results were compared with the activities of the earlier studied ethoxyquin (EQ; 1,2-dihydro-6-ethoxy-2,2,4-trimethylquinoline), a strong antioxidant used mainly as a preserva...

Journal: :Toxicology Letters 2021

• Pre-validation study on comet assay for detecting site of contact genotoxicity. Acrylic implants containing EMS (AF + EMS) was used as test item. AF showed DNA damage at using whereas negative Ames and chromosome aberration test. Implants may cause ‘site genotoxicity’ without systemic Comet has potential use in medical device biocompatibility assessment. Toxicological risk assessment devices ...

Journal: :Science 2001
T L Farnham D G Schleicher L M Woodney P V Birch C A Eberhardy L Levy

We analyzed photometric measurements and images of comet C/LINEAR before perihelion and after its breakup. Results from our photometry data include a lower limit of 0.44 kilometer for the radius of the nucleus before breakup, and a determination that it was depleted in carbon-chain molecules relative to most other comets. Our imaging and modeling results, which include a constraint on the rotat...

Journal: :Science 2011
Michael F A'Hearn Michael J S Belton W Alan Delamere Lori M Feaga Donald Hampton Jochen Kissel Kenneth P Klaasen Lucy A McFadden Karen J Meech H Jay Melosh Peter H Schultz Jessica M Sunshine Peter C Thomas Joseph Veverka Dennis D Wellnitz Donald K Yeomans Sebastien Besse Dennis Bodewits Timothy J Bowling Brian T Carcich Steven M Collins Tony L Farnham Olivier Groussin Brendan Hermalyn Michael S Kelley Jian-Yang Li Don J Lindler Carey M Lisse Stephanie A McLaughlin Frédéric Merlin Silvia Protopapa James E Richardson Jade L Williams

Understanding how comets work--what drives their activity--is crucial to the use of comets in studying the early solar system. EPOXI (Extrasolar Planet Observation and Deep Impact Extended Investigation) flew past comet 103P/Hartley 2, one with an unusually small but very active nucleus, taking both images and spectra. Unlike large, relatively inactive nuclei, this nucleus is outgassing primari...

Journal: :Science 2017
M Ramy El-Maarry O Groussin N Thomas M Pajola A-T Auger B Davidsson X Hu S F Hviid J Knollenberg C Güttler C Tubiana S Fornasier C Feller P Hasselmann J-B Vincent H Sierks C Barbieri P Lamy R Rodrigo D Koschny H U Keller H Rickman M F A'Hearn M A Barucci J-L Bertaux I Bertini S Besse D Bodewits G Cremonese V Da Deppo S Debei M De Cecco J Deller J D P Deshapriya M Fulle P J Gutierrez M Hofmann W-H Ip L Jorda G Kovacs J-R Kramm E Kührt M Küppers L M Lara M Lazzarin Z-Yi Lin J J Lopez Moreno S Marchi F Marzari S Mottola G Naletto N Oklay A Pommerol F Preusker F Scholten X Shi

The Rosetta spacecraft spent ~2 years orbiting comet 67P/Churyumov-Gerasimenko, most of it at distances that allowed surface characterization and monitoring at submeter scales. From December 2014 to June 2016, numerous localized changes were observed, which we attribute to cometary-specific weathering, erosion, and transient events driven by exposure to sunlight and other processes. While the l...

2017
Paula R. Williamson Douglas G. Altman Heather Bagley Karen L. Barnes Jane M. Blazeby Sara T. Brookes Mike Clarke Elizabeth Gargon Sarah Gorst Nicola Harman Jamie J. Kirkham Angus McNair Cecilia A. C. Prinsen Jochen Schmitt Caroline B. Terwee Bridget Young

The selection of appropriate outcomes is crucial when designing clinical trials in order to compare the effects of different interventions directly. For the findings to influence policy and practice, the outcomes need to be relevant and important to key stakeholders including patients and the public, health care professionals and others making decisions about health care. It is now widely ackno...

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